Year 2023 / Volume 115 / Number 6
Original
Health-related quality of life decline in clinically stable inflammatory bowel disease patients during the COVID-19 outbreak

315-319

DOI: 10.17235/reed.2022.8668/2022

Claudia Herrera-de Guise, Luis Fernando Mayorga Ayala, Xavier Serra Ruiz, Virginia Robles Alonso, Natalia Borruel Sainz, Arantxa Ibarz, Zahira Pérez Martínez, Francesc Casellas,

Abstract
Background and aims: Inflammatory bowel disease (IBD) affects many aspects of a patient’s life and impairs their health-related quality of life (HRQoL). The COVID-19 outbreak has led to important mobility restrictions and a dramatic re-adjustment of social habits and health systems. This study aimed to assess the influence of the outbreak and mobility restrictions on the HRQoL of IBD patients with stable clinical remission on biologic treatment. Their self-perceived stress scores during the outbreak were also assessed. Methods: A prospective, observational study was performed in IBD patients on biologic treatment with stable clinical remission. Patients with both Crohn’s disease and Ulcerative Colitis patients were included. Patients filled in the IBDQ9 and the Perceived stress scale (PSS) electronically. To determine any changes, the results of the IBDQ9 during the outbreak were compared with the last IBDQ9 before the outbreak. Results: 106 patients in clinical remission were included, with a median age of 42 year, 42% were female and 77% had CD. Median preCOVID-19 IBDQ9 was 72.1[66.5-80.12] and decreased to 69.2 [63.1-77.10] during the outbreak (p<0.001). The median PSS score was 12 [9-19]. There was a significant negative correlation between the PSS and the outbreak IBDQ9 (r=-0.66, p< 0.001). Regression analysis showed that the PSS score was associated with a lower IBDQ-9 during the outbreak(p<0.001) Conclusion: There was a negative impact of the COVID19 outbreak on the HRQoL of IBD patients in remission, with higher self-perceived stress scores associated with a lower QoL. The COVID-19 outbreak may have long-term implications for the HRQoL in these patients.
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Herrera-de Guise C, Mayorga Ayala L, Serra Ruiz X, Robles Alonso V, Borruel Sainz N, Ibarz A, et all. Health-related quality of life decline in clinically stable inflammatory bowel disease patients during the COVID-19 outbreak. 8668/2022


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Publication history

Received: 31/01/2022

Accepted: 09/03/2022

Online First: 17/03/2022

Published: 06/06/2023

Article revision time: 36 days

Article Online First time: 45 days

Article editing time: 491 days


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