Year 2022 / Volume 114 / Number 2
Letter
Apoptotic colopathy as a manifestation of Good’s syndrome

115-116

DOI: 10.17235/reed.2021.8297/2021

Margarita Rey, Daniela Rico, Rocío del Pilar López Panqueva, Mariana Vásquez Roldán,

Abstract
The case was a 44-year-old patient with four years of evolution of respiratory infections, fever, weight loss of 30 kg and chronic diarrhea with inconclusive colonoscopy studies, managed as inflammatory bowel disease (IBD), with a history of thymomectomy four years previously. On physical examination, there was severe protein-calorie malnutrition, skin lesions compatible with herpes simplex infection and lower limb edema. Blood tests were requested when pancytopenia and hypoalbuminemia were negative for human immunodeficiency virus (HIV). Chest tomography showed a budding tree pattern and bronchiectasis, but SARS-CoV-2 was negative. A colonoscopy was performed, showing the presence of ulcers in the sigmoid colon with an infectious aspect vs IBD.
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References
1. Qu J, Lü X, Gao Q, Zhang Y. Good Syndrome, a Rare Cause of Refractory Chronic Diarrhea and Recurrent Pneumonia in a Chinese Patient after Thymectomy. Clin Vaccine Immunol CVI. 2013 Jul;20(7):1097–8. DOI: 10.1128/CVI.00141-13
2. Jansen A, van Deuren M, Miller J, Litzman J, de Gracia J, Sáenz-Cuesta M, et al. Prognosis of Good syndrome: mortality and morbidity of thymoma associated immunodeficiency in perspective. Clin Immunol. 2016 Oct;171:12–7. DOI: 10.1016/j.clim.2016.07.025
3. Campos-Murguía A, Marfil-Garza BA, León-Lara X, Jiménez Gutiérrez JM, Botello-Partida SL. A Patient With Good Syndrome Complicated With Phlegmonous Gastritis. ACG Case Rep J. 2019 Oct 17;6(10):e00246. DOI: 10.14309/crj.0000000000000246
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Rey M, Rico D, López Panqueva R, Vásquez Roldán M. Apoptotic colopathy as a manifestation of Good’s syndrome. 8297/2021


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Publication history

Received: 24/08/2021

Accepted: 30/08/2021

Online First: 07/09/2021

Published: 07/02/2022

Article revision time: 4 days

Article Online First time: 14 days

Article editing time: 167 days


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