Year 2022 / Volume 114 / Number 5
Original
Perianal Crohn’s disease: clinical implications, prognosis and use of resources

254-258

DOI: 10.17235/reed.2021.7918/2021

Elia Rosa Martínez Sánchez, Ana Solá Fernández, Domingo Pérez Palacios, Andrea Núñez Ortiz, María Dolores de la Cruz Ramírez, Eduardo Leo Carnerero, Claudio Trigo Salado, José Manuel Herrera Justiniano,

Abstract
Objective: to investigate the prevalence of perianal disease, the associated phenotypical factors, its influence on prognosis and its impact on the use of health resources for patients with Crohn’s disease. Methods: a unicentric retrospective observational study was performed with 430 patients with Crohn’s disease tracked through a monographical consultation of intestinal inflammatory disease. Demographic and phenotypical data of Crohn’s disease, pharmacological and surgical treatments, complementary tests carried out and hospital admissions were analyzed. A comparative study between those patients without perianal disease and those with perianal disease was performed, both in simple form and complex form. Results: the prevalence of perianal disease was 40.2 %, and fistulas and abscesses were the most frequent manifestations. These appearances were associated with an affected rectum and the existence of extra-intestinal manifestations. The patients with perianal disease most frequently required immuno-suppressant and biological treatment, but no further abdominal surgery. Amongst the patients with perianal disease, the need for biologics was more frequent for luminal disease (42.8 % vs 30.7 %). Furthermore, more explorations were needed, aimed at the study of perianal disease and recto-colonoscopies, although more magnetic resonance (MR)/computed tomography (CT) enterographies were not required. Conclusions: perianal disease has a high prevalence among patients with Crohn’s disease, especially when the rectum is affected. It is associated with a worse prognosis and more frequently requires biological treatments due to perianal and luminal evolution, especially in cases of complex perianal disease. This condition calls for more hospital admissions and complementary tests.
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Martínez Sánchez E, Solá Fernández A, Pérez Palacios D, Núñez Ortiz A, de la Cruz Ramírez M, Leo Carnerero E, et all. Perianal Crohn’s disease: clinical implications, prognosis and use of resources. 7918/2021


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Publication history

Received: 23/02/2021

Accepted: 06/07/2021

Online First: 24/08/2021

Published: 06/05/2022

Article revision time: 132 days

Article Online First time: 182 days

Article editing time: 437 days


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