Year 2023 / Volume 115 / Number 11
Letter
Severe outbreak of ulcerative colitis and cerebral neoplasia. Difficult management in COVID time

657

DOI: 10.17235/reed.2023.9527/2023

Samer Mouhtar El Hálabi, Teresa Valdés Delgado, Belén Maldonado Pérez, María Belvis Jiménez, Federico Argüelles Arias,

Abstract
A 61-year-old male diabetic patient, diagnosed with ulcerative colitis (UC) 30 years ago, currently under treatment with mesalazine is presented. He was admitted to the emergency department due to a severe outbreak of UC, with 15 depositions daily, rectal bleeding and poor general condition. A brain CT-scan was carried out in the emergency department due to a sudden self-limited aphasia. A left frontal lesion of 45x38 mms with a prominent perilesional edema and with a displacement of the midline was reported. This was believed to be a meningioma (figure 1A). Urgent neurosurgery was not performed, prioritizing the severe flare-up UC. Based on this, full-dose metilprednisolone was administered.
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References
1. Sicilia B, García-López S, González-Lama, et al. Guía GETECCU 2020 para el tratamiento de la colitis ulcerosa. Gastroenterol Hepatol. 2020;43(Supl 1):1-57.
2. Bonovas S, Fiorino G, Allocca M, et al. Biologic Therapies and Risk of Infection and Malignancy in Patients with Inflammatory Bowel Disease: A Systematic Review and Network Meta-analysis. Clin Gastroenterol Hepatol. 2016 Oct;14(10):1385-1397
3. Chaparro M, Ramas M, Benítez JM, et al. Extracolonic cancer in inflammatory bowel disease. Data from the GETECCU Eneida Registry. Am J Gastroenterol. 2017; 112: 1135-43.
4. Nalatagla N, Falloon K, Tran G, et al. Effect of Accelerated infliximab induction on short- and longterm outcomes of acute severe ulcerative colitis: A retrospective multi-center study meta-analysis. Clin Gastroenterol Hepatol. 2019 February ; 17(3): 502–509.
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Mouhtar El Hálabi S, Valdés Delgado T, Maldonado Pérez B, Belvis Jiménez M, Argüelles Arias F. Severe outbreak of ulcerative colitis and cerebral neoplasia. Difficult management in COVID time. 9527/2023


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Publication history

Received: 13/02/2023

Accepted: 21/02/2023

Online First: 17/03/2023

Published: 13/11/2023

Article Online First time: 32 days

Article editing time: 273 days


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