Year 2025 / Volume 117 / Number 10

Editorial
547-553
DOI: 10.17235/reed.2025.11636/2025
Javier Crespo, Conrado M. Fernández Rodríguez, María Dolores Martín Arranz, Luis Téllez, Federico Argüelles-Arias, Aitor Orive, Eduard Espinet,
Obesity represents the most prevalent chronic metabolic disease and one of the greatest healthcare and social challenges of our time. Its close association with multiple digestive disorders—including metabolic...
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Editorial
554-556
DOI: 10.17235/reed.2025.11670/2025
Federico Argüelles-Arias, Joaquín Poza Cordón, María Dolores Martín Arranz, Luis Téllez, Julio Iglesias-García, Marisa Iborra, Judith Gómez-Camarero, Aitor Orive, Rafael Gómez Rodríguez,
The Spanish Society of Digestive Diseases (SEPD) and the Spanish Association of Digestive Ultrasound (AEED), as leading scientific societies in the field of Gastroenterology in Spain, have among their...
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Original
557-563
DOI: 10.17235/reed.2025.11335/2025
Lucía Cayuela, Victoria Achaval, Gema Flox-Benítez, Aurelio Cayuela Domínguez,
Background: this study examines the trends in pancreatic cancer (PC) incidence in Spain from 1992 to 2021, focusing on sex and age-specific patterns and the influence of age, period, and birth cohort. Methods:...
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Original
564-571
DOI: 10.17235/reed.2025.11389/2025
Lucía Cayuela, Victoria Achaval, Gema Flox-Benítez, Aurelio Cayuela Domínguez,
Background: this study analyses mortality trends in early-onset gastrointestinal cancers (EOGIC, < 50 years) in Spain between 1999 and 2023, comparing them with those of late-onset cancers (≥ 50 years). Methods:...
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Special Article
572-578
DOI: 10.17235/reed.2025.11310/2025
Marta Pascual-Mato, Gabriel Gárate Viñas, María Muñoz San Martín, Vicente González-Quintanilla, Javier Crespo, Montserrat Rivero Tirado, Julio Pascual Gómez,
The concept “gut-brain axis” means a bidirectional communication between the central nervous system and the gastrointestinal (GI) tract. This axis is key in keeping the physiological homeostasis of the...
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Digestive Diseases Image
579-580
DOI: 10.17235/reed.2024.10125/2023
André Gonçalves, Carina Leal, Isabel Cotrim, Helena Vasconcelos,
Pancreatobiliary fistulas associated withntraductal Papillary Mucinous Neoplasm (IPMN) are rare and present therapeutic challenges. The authors describe the clinical course of an 81-year-old woman presenting...
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Digestive Diseases Image
581-583
DOI: 10.17235/reed.2024.10067/2023
Carlos Alventosa Mateu, Laura García Llabata, Brian Herráez Cervera, Juan José Urquijo Ponce,
Transarterial chemoembolization of hepatocellular carcinoma consists of the selective release of chemotherapeutic agents in the tumor feeding arteries (and their subsequent occlusion) and presents a low...
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Digestive Diseases Image
584-585
DOI: 10.17235/reed.2024.10134/2023
Mara Sarmento Costa, Marta Gravito-Soares, Elisa Gravito-Soares, Pedro Figueiredo,
An 88-year-old man presented with haematemesis with haemodynamic stability requiring transfusion of 5 units of blood. Physical examination was unremarkable. Upper endoscopy identified a fistulous opening...
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Letter
586-587
DOI: 10.17235/reed.2024.10440/2024
Yaot-Ting Li, Li-Chao Zhang, Ting-Ting Yu, Jiao Tian, Yan-Kun Hou, Sen-Lin Hou,
Pancreatic cutaneous fistula is a complex condition, making it challenging to achieve favorable outcomes with conservative medical treatment. Surgical interventions often entail surgical risks and postoperative...
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Letter
587-588
DOI: 10.17235/reed.2024.10609/2024
Yimin Ma, Fang Wang, Xiaolu Yu, zhenguo qiao,
A 37-year-old patient presented to our hospital for upper endoscopy with upper abdominal pain for 10 days. The gastroscopy showed food retention, a large ulcer from the corner of the stomach to the stomach...
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Letter
588-589
DOI: 10.17235/reed.2024.10617/2024
Julio César Moreno-Alfonso, Sharom Barbosa-Velásquez, Ada Molina Caballero, Alberto Pérez Martínez, María Concepción Yárnoz Irazábal,
Up to 20% of advanced appendicitis cases can be complicated by postoperative abscesses, adding morbidity and mortality and prolonging hospital stays. This study examines the utility of two cellular indices...
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Letter
589-590
DOI: 10.17235/reed.2024.10596/2024
Silvia Fernández Noël, Óscar García Villar, Audrey Jiménez Torres, Nicolás Pareja Arico, Julia Gutiérrez de Prado, Óscar Caso Maestro, Francisco J. García Borda, Eduardo Ferrero Herrero,
Wilkie’s syndrome, also known as Superior mesenteric artery (SMA) syndrome, is characterized by intestinal obstruction due to aortomesenteric duodenal compression caused by the reduction of the normal...
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Letter
591
DOI: 10.17235/reed.2023.10056/2023
Wei Zhang, Sen-Lin Hou, Li-Chao Zhang,
It is not uncommon to encounter difficult cannulation during endoscopic retrograde cholangiopancreatography (ERCP), most of which can be performed by double-guide wire, pre-cut and other techniques. Endoscopic...
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Letter
592-593
DOI: 10.17235/reed.2024.10624/2024
Sabri Selcuk Atamanalp, Esra Disci, Rifat Peksoz, Enes Agirman,
We report the case of a 74-year-old male with abdominal pain, distention and obstipation for 8 hours. He had a medical history of 24 sigmoid volvulus (SV) episodes, 23 of which treated with endoscopic...
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Letter
593-594
DOI: 10.17235/reed.2023.9973/2023
Carlos Miguel Chavarría Herbozo, Lorena Sancho-del Val, Cristina Cuadrado-Tiemblo, Cristina Vicente Martín, Luis Wong Becerra, Daniel Riado Mínguez,
Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) is recommended as a rescue treatment of malignant distal biliary obstruction (MBDO) after failed ERCP and endoscopic ultrasound-guided biliary...
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Letter
594-595
DOI: 10.17235/reed.2024.10579/2024
Bárbara Segura-Méndez, Álvaro Fuentes-Martín, Yolanda Carrascal,
We present a case of a 55-year-old male, presenting with angina symptoms with electrocardiographic changes and a panfocal systolic murmur radiating to the carotids. He had a primary HBV infection 8 months...
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Letter
595-596
DOI: 10.17235/reed.2023.10022/2023
Guinan Liu, Wenhui Wu, Xiaodong Jiang, Xuankai Liao, Liyuan Lv,
A 46-year-old male visited our hospital with blood stool and constipation. Colonoscopy revealed a broad-based protruded lesion in the rectum.The endoscopic ultrasonography showed the lesion invaded the...
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Letter
596
DOI: 10.17235/reed.2023.10031/2023
Ignacio Fernández Hurtado, Naila Pagés Valle, Santiago Baena Bradaschia, Enrique Colás Ruiz, Marta Castro Suárez, José Andrés Cifuentes Ródenas,
We are thrilled to present a new technique for treating chronic anal fissures using ultrasound-guided botulinum toxin injections. Our approach involves injecting botulinum toxin into the internal anal...
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Letter
597-598
DOI: 10.17235/reed.2024.10642/2024
Julio César Moreno-Alfonso, Sharom Barbosa-Velásquez, Ada Molina Caballero, Alberto Pérez Martínez, María Concepción Yárnoz Irazábal,
Between 16-40% of patients present with complicated appendicitis at the time of diagnosis, making early suspicion of appendicular perforation key for initiating timely treatment and reducing morbidity...
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Letter
598-599
DOI: 10.17235/reed.2024.10647/2024
Yu Tang, Huiwei Zhang, Lijuan Ren, Min Xie, Ke Liu, Lizhi Yi, Xiaoling Zhou, Xianfei Zhong,
A 72-year-old female who had received emergent endoscopic cyanoacrylate (CYA) injection for bleeding gastric varices (GV) two month before was readmitted due to recurrence of melena. Current gastroscopy...
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Letter
599-600
DOI: 10.17235/reed.2024.10906/2024
Joaquín González Aroca,
Preoperative rehabilitation, or prehabilitation, plays a crucial role in improving outcomes for patients undergoing complex surgeries like pancreaticoduodenectomy. In the article “Prehabilitation in Patients...
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Letter
600-601
DOI: 10.17235/reed.2024.10535/2024
Marta Fernández Carrasco, Olga Sánchez García, Ana Plaza Fernández,
Acquired chronic hepatocerebral degeneration (CAHD) is a rare and irreversible neurological disorder that can occur in patients with chronic liver disease. It is characterized by neurological symptoms...
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Letter
601-602
DOI: 10.17235/reed.2024.10638/2024
Maki Setake, Mami Tomiyama, Kyoko Arakaki, Akira Hokama,
A 49-year-old man presented for a screening esophagogastroduodenoscopy (EGD) as part of his registration for a donated kidney transplant. He had been on hemodialysis for 4 years for end-stage renal disease...
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Letter
602-603
DOI: 10.17235/reed.2024.10756/2024
Andrea García Soria, Alicia Brotons Brotons, Julia Sáez Fuster, Víctor Argumánez Tello, Mariana Fe García Sepulcre, Javier Sola-Vera Sánchez,
Esophageal squamous cell carcinoma (ESCC) remains the most prevalent subtype of esophageal cancer worldwide. Major risk factors include chronic alcohol consumption and heavy smoking. We present the case...
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Letter
603-604
DOI: 10.17235/reed.2024.10775/2024
Zhen Liu, Jia Feng, Haifeng Jin, Quanhui Chen,
A 57-year-old woman presented to our hospital with chest distension, sore throat and back discomfort beginning the previous day after taking 5 panax notoginseng capsules. She had a history of hypertension...
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Letter
604-605
DOI: 10.17235/reed.2024.10622/2024
Chen Yuan, Youhong Cao, Yiyang Zhang, Yimin Ma, Fang Wang,
A 67-year-old male was admitted to our hospital with a diagnose of a <1-cm clear dehiscence orifice at the gastroesophageal anastomosis. Considering of the cachexia state and the size of fistula, a new...
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Letter
605-607
DOI: 10.17235/reed.2024.10875/2024
Víctor González Pintor, Elena Resina Sierra, Sergio Casabona Francés, María Teresa Pérez Fernández, Marta Hermida Lario, Lingyu Xu Xu, Luis Gerardo Alcalá González, Cecilio Santander Vaquero,
Chronic intestinal pseudo-obstruction (CIPO) is a rare condition affecting the motility of the lower gastrointestinal tract, while achalasia is an uncommon esophageal motility disorder. The coexistence...
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Letter
608-609
DOI: 10.17235/reed.2025.11077/2025
Wei Zhang, Jiao Tian, Sen-Lin Hou, Yan-Kun Hou, Li-Chao Zhang,
Biliary signet-ring cell carcinoma is a rare malignant tumor of the biliary tract. signet-ring cell carcinoma often occurs in the gastrointestinal tract. In this case, we can intuitively see the location,...
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Letter
609-610
DOI: 10.17235/reed.2025.11078/2025
Raquel Gómez Perosanz, Marta Quiñones Calvo,
A 37-year-old HIV-positive male with a history of cutaneous Kaposi’s sarcoma (KS) presented with chronic bloody diarrhea, abdominal pain, and weight loss despite an undetectable viral load and a CD4 count...
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Letter
610-611
DOI: 10.17235/reed.2025.11060/2025
Yongzhan Zhao, Longwei Fang, Yuxi Zhang, Tingting Yu, Lichao Zhang, Senlin Hou,
When Endoscopic retrograde cholangiopancreatography (ERCP) fails in patients with obstructive jaundice, EUS-guided rendezvous technique (EUS-RV) becomes an alternative treatment. For the EUS-RV, we can...
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Letter
611-612
DOI: 10.17235/reed.2025.11248/2025
Ming Zhong, Wei Wei, Tingyu Wang, Huang Zhong, Hang Gong,
A 75-year-old man presented to our department, complaining of recurrent abdominal pain for the past month. Esophagogastroduodenoscopy (EGD) revealed a single 0.6 cm polypoid lesion, classified as Yamada...
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Letter
612-613
DOI: 10.17235/reed.2025.11292/2025
Adriana Fuentes Gómez,
The letter highlights the growing issue of misinterpretation of the breath test in diagnosing SIBO, particularly in patients with slow intestinal transit. It warns of the risk of false negatives when key...
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Letter
613-614
DOI: 10.17235/reed.2024.10778/2024
Julio César Moreno-Alfonso, Sharom Barbosa-Velásquez, Ada Molina Caballero, Alberto Pérez Martínez, María Concepción Yárnoz Irazábal,
Crohn's disease (CD) is a type of inflammatory bowel disease (IBD) characterized by chronic, transmural, and relapsing inflammation that can affect any segment of the gastrointestinal tract, from the oral...
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Letter
614-615
DOI: 10.17235/reed.2024.10786/2024
Fang Wang, Zhifeng Li, Xinqing Lu, Hongfei He, Shaoqiong Cheng, Jialei Chang, Xinghua Peng,
Postoperative biliary stricture after biliary surgery is a challenging condition. Biliary stent placement by endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound (EUS) are the...
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Letter
615-616
DOI: 10.17235/reed.2024.10812/2024
Julio César Moreno-Alfonso, Sharom Barbosa-Velásquez, Ada Molina Caballero, Alberto Pérez Martínez, María Concepción Yárnoz Irazábal,
Eosinophilic esophagitis (EoE) is an immune-mediated disorder of the esophagus with a broad spectrum of clinical presentations. Dysphagia and food impaction are the cardinal symptoms; however, their diagnostic...
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Letter
617-618
DOI: 10.17235/reed.2024.10834/2024
Julio César Moreno-Alfonso, Miguel Ángel Sánchez Durán, Sharom Barbosa-Velásquez, Ada Molina Caballero, Alberto Pérez Martínez, María Concepción Yárnoz Irazábal,
Ulcerative colitis (UC) is a chronic, relapsing inflammatory bowel disease (IBD) of the colon. Its presentation is varied, with the main symptoms being mucosanguineous diarrhea, abdominal pain, and weight...
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Letter
618-619
DOI: 10.17235/reed.2024.10848/2024
Joaquín González Aroca,
In response to the study by Tian et al. on the immunogenicity of COVID-19 vaccines in patients with autoimmune hepatitis, this letter commends the authors' contribution but highlights a critical omission:...
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Letter
619-620
DOI: 10.17235/reed.2024.10859/2024
Sandra Borrego Rivas, Alia Martín Izquierdo, Patricia Suárez Álvarez, Irene Latras Cortés, Mónica Sierra Ausín,
Protein-losing enteropathy is a relatively uncommon syndrome characterized by excessive loss of proteins into the intestinal lumen. It can be caused by various etiologies. Inflammatory bowel disease (IBD)...
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Letter
620-621
DOI: 10.17235/reed.2024.10861/2024
Julio César Moreno-Alfonso, Sara Pérez Ollo, Sharom Barbosa-Velásquez, Ada Molina Caballero, Alberto Pérez Martínez, María Concepción Yárnoz Irazábal,
Crohn's disease (CD) is a relapsing-remitting inflammatory bowel disease (IBD) affecting the gastrointestinal tract. Its symptoms are nonspecific, with weight loss, diarrhea, and abdominal pain being classic,...
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Letter
621-622
DOI: 10.17235/reed.2024.10819/2024
Alberto Gómez Gómez, Cristina Espuche Jiménez, Manuel Romero Martínez, Germán Morales López, Lorena Tudela Quiñonero,
We present the case of a 73-year-old male, recipient of a liver transplant a year ago, with migration of a “Be-Graft” stent used in a pre-transplant transjugular intrahepatic portosystemic shunt towards...
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Letter
622-623
DOI: 10.17235/reed.2024.10800/2024
Álvaro Cerezuela Fernández de Palencia, David Ruiz de Angulo Martín, Vicente Munitiz Ruiz, Ana Conesa Pla, Juan Egea Valenzuela, Miriam Alajarin Cervera, María Muñoz Tornero, Luisa Fernanda Martínez de Haro,
Dehiscence following esophagectomy for cancer has a mortality rate of 10-40%, prolongs hospital stay, and reduces survival. To prevent it, proper patient selection and surgical techniques that minimize...
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Letter
623-625
DOI: 10.17235/reed.2024.10903/2024
Wei Zhang, Jiao Tian, Sen-Lin Hou, Yan-Kun Hou, Li-Chao Zhang,
The incidence of hilar cholangiocarcinoma is (1-2) / 100,0001. Due to the high location of obstruction, the treatment of hilar cholangiocarcinoma is complicated, especially for patients with gastrointestinal...
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The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
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