Year 2025 / Volume 117 / Number 8

Editorial
423-425
DOI: 10.17235/reed.2025.11371/2025
Javier Crespo, Agustín Albillos, María Buti,
April 2025 marks the 10th anniversary of the Strategic Plan for Addressing Hepatitis C (PEAHC). The inception of PEAHC arose from the necessity to secure funding for the new direct-acting oral antiviral...
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Original
426-432
DOI: 10.17235/reed.2025.10983/2024
Haiya Ou, Zhiming Lai, Xiaopeng Ye, Xiaotong Wang, Haixiong Lin,
Background and aims: the relationship between irritable bowel syndrome (IBS) and structural changes in various regional cortical areas remains unclear. Mendelian randomization (MR) was used to explore...
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Original
433-440
DOI: 10.17235/reed.2025.11157/2025
Sandra Izquierdo Santervás, Carlos Maroto Martín, Aida Fiz-López, José Antonio Garrote Adrados, Sara Cuesta Sancho, David Bernardo Ordiz, Eduardo Arranz Sanz, Luis Fernández-Salazar,
Background: the high prevalence of disorders of the gut-brain interaction (DGBI), the availability of breath tests for the diagnosis of small intestine bacterial overgrowth (SIBO) together with some confusion...
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Original
441-446
DOI: 10.17235/reed.2025.11101/2025
Esteban Fuentes-Valenzuela, Sergio Escribano Cruz, Javier Parra Villanueva, Almudena Calvache Rodríguez, Ariadna Gil Díaz, María del Carmen López-Martín, Itziar Rubio de la Plaza, Santiago Blanco, Irene Chivato Martín-Falquina, Beatriz Rodríguez-Batllori Aran, Raquel Latorre Martinez, Luis Alonso Castillo Herrera, Rafael Olvera, Daniel Alcalde Rodríguez, Karina Guzmán López, Alicia Bejerano Domínguez,
Introduction: There is growing interest in autoimmune gastritis (AIG), particularly regarding its prevalence and natural history. Methods. A retrospective observational study was performed, including...
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Original
447-454
DOI: 10.17235/reed.2025.11158/2025
Beatriz Gros, Paloma Elma Alañón Martínez, Marina Orti Cuerva, Ana Aparicio-Serrano, Elma Gallego Jiménez, Ana Santos Lucio, María Pleguezuelo Navarro, Antonio Hervás Molina, Francisco Javier Serrano Ruiz,
Background: biliary brushing cytology during endoscopic retrograde cholangiopancreatography (ERCP) was used to assess the nature of a biliary stricture. Its low sensitivity challenges the exclusion of...
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Digestive Diseases Image
455-456
DOI: 10.17235/reed.2023.10086/2023
Isabel Tarrio, Tarcísio Araújo, João Fernandes, Luís Lopes,
A 50-year-old woman with a history of bicuspid aortic valve (BAV) and ascending aorta dissection was referred for endoscopic ultrasound (EUS) for suspected choledocholithiasis. Twelve years earlier she...
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Digestive Diseases Image
457-458
DOI: 10.17235/reed.2023.10097/2023
Andreia Rei, Irina Mocanu, Carlos Pontinha, Isabel Medeiros,
This case reports illustrates a 44-year-old Caucasian male with ileal Crohn´s disease under combined immunosuppression that first presented with unspecific constitutional symptoms, newly pancytopenia and...
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Digestive Diseases Image
459-460
DOI: 10.17235/reed.2023.10087/2023
Isabel Tarrio, Alda João Andrade, Marta Moreira, Luís Lopes,
An 82-year-old man was admitted for acute cholangitis. He presented with jaundice and elevated hepatic cholestasis enzymes and C-reactive protein. Abdominal ultrasound and CT scan showed no evidence of...
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Letter
461-462
DOI: 10.17235/reed.2024.10506/2024
Su Luo, Ben-Hua Wu, Li-Sheng Wang,
Duodenal-type follicular lymphoma (D-FL) is a special type of follicular lymphoma, which tends to occur in the descending segment of the duodenum. The lesion is mostly limited to the mucosal layer. The...
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Letter
462-463
DOI: 10.17235/reed.2024.10644/2024
Qian Zhang, Jun Liu, Hui Yang, Chaowu Chen,
Mantle cell lymphoma (MCL) is an aggressive B-cell lymphoma that occurs in some patients with gastric and intestinal involvement, but esophageal involvement is rare, and involvement of the entire gastrointestinal...
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Letter
463-464
DOI: 10.17235/reed.2024.10672/2024
Zhi-Chao Yu, Rui-Yue Shi, Qin Yan, Jun Yao, Li-Sheng Wang, Ben-Hua Wu,
A biliary stricture is an abnormal narrowing in the ductal drainage system of the liver. There are many etiologies of biliary stricture, the most common and ominous of which is malignancy, either primary...
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Letter
464-466
DOI: 10.17235/reed.2024.10652/2024
De-Feng Li, Yan-Hui Tian, Rui-Yue Shi, Ding-Guo Zhang,
Endoscopic treatment is generally recommended for the duodenal epithelial adenoma. Although underwater endoscopic mucosal resection (UEMR) has become established as an effective modality for the superficial...
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Letter
466-467
DOI: 10.17235/reed.2024.10633/2024
Irene González Díaz, María Carmen Méndez, Mariana Tavecchia, Carmen Amor Costa, Clara Amiama Roig, Aurora Burgos García,
Gastritis cystica profunda (GCP) is a rare entity characterized by foveolar hyperplasia and cystic dilation of the gastric mucosa and submucosal glands. Its etiopathogenesis remains unknown. It has been...
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Letter
467-468
DOI: 10.17235/reed.2024.10710/2024
Wanshuang Ye, Chen-Chen Nie, Yuli Zeng,
Concurrent occurrence of hemangioendothelioma in the spleen and liver of a 1-year-old child is a rare clinical case.She had a history of good health. Laboratory tests showed elevated inflammatory markers,...
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Letter
468-469
DOI: 10.17235/reed.2024.10733/2024
Yuxuan Mao, Weinan Liu, Yuping Yao, Chen Zou, Binzhang Tian,
Epithelioid hemangioendothelioma (EHEs) is a vascular endothelial-derived tumor, which can be seen in the liver, mediastinum, lung and other parts, and most often occurs in the liver. Hepatic epithelioid...
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Letter
469-470
DOI: 10.17235/reed.2024.10540/2024
David Luengo Gómez, Ángela Salmerón Ruíz, Javier Pastor Mena, Antonio Jesús Láinez Ramos-Bossini,
Lymphoepithelioma-like carcinoma (LELC) is a histological variant that resembles nasopharyngeal lymphoepithelioma and occurs in various locations such as the salivary glands and lung. LELCs in the digestive...
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Letter
470-471
DOI: 10.17235/reed.2024.10551/2024
Luís Correia Gomes, Marta Moreira, Isabel Tarrio, Alda João Andrade, Tarcísio Araújo, Jorge Canena, Luís Lopes,
77-year-old female with history of cholecystectomy was admitted at emergency department with fever and myalgia, without other complaints. Physical examination revealed fever, and laboratory tests indicated...
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Letter
471-472
DOI: 10.17235/reed.2024.10544/2024
Wanshuang Ye, Chengcheng Nie, Yuli Zeng,
A 48-year-old woman was incidentally found to have a pancreatic mass during a health examination.In the past, she had been in good physical health. Laboratory investigations including tumor markers and...
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Letter
472-473
DOI: 10.17235/reed.2024.10550/2024
Samuel Robles Gaitero, Jorge del Río-Fernández, Sagrario María Santos-Seoane, Teresa Sampedro-Gimeno, Javier Tejedor-Tejada, Ana Villar Caamaño, Cristina Camblor, Cristina Menéndez Sánchez,
We present the case of a 52-year-old woman diagnosed with stage IV clear cell renal cell carcinoma who received combination of surgery and systemic therapy with nivolumab (anti-PD1) and ipilimumab (anti-CTLA-4)....
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Letter
473-474
DOI: 10.17235/reed.2024.10552/2024
Maria José Temido, Luís Santos, Elisa Gravito-Soares, Marta Gravito-Soares, Pedro Amaro, Maria Augusta Cipriano, Pedro Figueiredo,
Endoscopic full-thickness resection (eFTR) is an emerging technique that enables effective and safe management of complex colorectal lesions. The full-thickness resection device (FTRD®, Ovesco, Germany)...
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Letter
475-476
DOI: 10.17235/reed.2024.10554/2024
Raquel R. Mendes, Pedro C. Figueiredo,
Self-expandable metal stents (SEMS) have been widely used for the palliation of esophageal malignant dysphagia. Stent-related dysphagia is frequent and should raise the suspicion of stent migration, tumor...
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Letter
476-477
DOI: 10.17235/reed.2024.10538/2024
Eduany Hernández, Javier Tejedor-Tejada, Laura Sánchez Sanmamed, Cristina Camblor, Ana Villar Caamaño, Samuel Robles Gaitero, Esmeralda Groba,
Adenocarcinoma accounts for 90% of malignant gastric tumours. Lymphomas, gastrointestinal stromal tumours (GIST) and other less frequent tumours account for 10%. However, rhabdomyosarcoma (RMS) remains...
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Letter
477-478
DOI: 10.17235/reed.2024.10536/2024
Alan Rafael Jiménez Rodríguez, Carlos Eugenio González Martínez, Diego García-Compeán, Héctor Jesús Maldonado Garza,
A 66-year-old female presented to our hospital with diffuse abdominal pain and diarrhea. An abdominal CT showed a splenic abscess of 9.9 x 6.1 x 6.5 cm. A conservative approach with US-guided percutaneous...
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Letter
478
DOI: 10.17235/reed.2024.10878/2024
Sandra Borrego Rivas, Alia Martín Izquierdo, Cristina Pisabarros Blanco, Jesús Espinel Díez,
The most common extranodal localization of lymphomas is the small intestine, with large B-cell lymphoma and MALT lymphoma being the most typical types. Intestinal follicular lymphomas are an infrequent...
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Letter
479-481
DOI: 10.17235/reed.2024.10933/2024
Pengwei Liu, Yan Zhang,
Recently, mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) have attracted more attention. However, early gastric MiNEN is uncommon, and there are rare reports on the characteristics of it. As...
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Letter
481-482
DOI: 10.17235/reed.2025.11408/2025
Cong Dai, Yu-Hong Huang,
Severe oral and gastrointestinal mucositis, though rare with immune checkpoint inhibitors, represents a life-threatening immune-related adverse events (irAE) requiring prompt recognition1,2. Key diagnostic...
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Letter
483-484
DOI: 10.17235/reed.2024.10784/2024
Ana López-Mourelle, Miriam Rubiera, Pablo Argüelles-Estrada, Sara Lamas-Álvarez, Fernando Fernández Cadenas,
Plasmablastic lymphoma (PBL) is an aggressive and rare variant of diffuse large B-cell lymphoma associated with human immunodeficiency virus (HIV) infection. Here, we describe a case of PBL of the ascending...
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Letter
484-485
DOI: 10.17235/reed.2024.10917/2024
Joaquín González Aroca,
Mendelian randomization (MR) offers a more rigorous framework than traditional observational studies by using genetic variants to assess causal relationships. Three critical assumptions are necessary for...
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Letter
485
DOI: 10.17235/reed.2024.10936/2024
Cong Gao, Shengwu Chuai, Zhendong Liang, Chun Ye, Xingshun Qi,
Meckel’s diverticulum, the most common congenital anomaly of the gastrointestinal tract, is often asymptomatic. Lack of complete resorption of the omphalomesenteric duct is an important cause of Meckel’s...
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Letter
485-486
DOI: 10.17235/reed.2024.10741/2024
Zheng Li, Sen-Lin Hou, Lichao Zhang, Haiming Du,
Postoperative anastomotic stenosis is a common complication after biliary, pancreatic and gastrointestinal surgery, which may be caused by multiple factors such as tissue proliferation and cancer recurrence....
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