Año 2017 / Volumen 109 / Número 12
Original
Enteral nutrition is associated with a decreased risk of surgical intervention in Crohn’s disease patients with spontaneous intra-abdominal abscess

834-842

DOI: 10.17235/reed.2017.5116/2017

Xiao-Bin Zheng, Xiang Peng, Xiao-Yu Xie, Lei Lian, Xian-Rui Wu, Jian-Cong Hu, Xiao-Wen He, Jia Ke, Yu-Feng Chen, Min Zhi, Xiao-Jian Wu, Xiao-Sheng He, Ping Lan,

Resumen
Background: The impact of enteral nutrition (EN) on surgical risk in Crohn’s disease (CD) patients suffering from spontaneous intra-abdominal abscess (IAA) was evaluated. Methods: CD patients diagnosed with spontaneous IAA from 2008 to 2015 were included in the study. The impact of EN on surgical risk was evaluated using both univariate and multivariate analyses. Results: A total of 87 patients were enrolled, 66 (75.9%) were male. The mean age at the development of an abscess was 30.2 ± 10.1 years and the median duration of illness from CD diagnosis until the development of an abscess was three (2-6) years. After a median follow-up of 1.9 (1.1-2.9) years, surgical intervention was performed in 42 patients (48.3%). Patients treated with EN were less likely to require surgical intervention (26.1% vs 56.3%, p = 0.01). Multivariate analysis showed that EN was an independent protective factor for the risk of surgery with a hazard ratio of 0.27 (95% confidence interval: 0.11-0.65, p = 0.004) after adjusting for abdominal pain, history of abdominal surgery, concomitant intestinal stenosis and prior use of antibiotics within three months. Conclusions: Surgical intervention is common for CD patients with IAA. Appropriate application of EN may help obviate the need for surgical treatment.
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Bibliografía
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Zheng X, Peng X, Xie X, Lian L, Wu X, Hu J, et all. Enteral nutrition is associated with a decreased risk of surgical intervention in Crohn’s disease patients with spontaneous intra-abdominal abscess. 5116/2017


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Recibido: 10/06/2017

Aceptado: 31/07/2017

Prepublicado: 05/10/2017

Publicado: 04/12/2017

Tiempo de revisión del artículo: 45 días

Tiempo de prepublicación: 117 días

Tiempo de edición del artículo: 177 días


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