Year 2017 / Volume 109 / Number 9
Letter to the Editor
Long survival in a patient with metastatic colorrectal carcinoma: reality or utopia?

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DOI: 10.17235/reed.2017.4817/2016

Andrea Illán, Jonathan Aires, Laura Quintana,

Abstract
We report the case of a 42-year-old male patient with mucinous-type metastatic colorectal carcinoma of eight years of evolution. He has received multiple lines of cytostatic treatment with acceptable tolerance and without significant impairment in his quality of life. At present, it is estimated that the overall survival of metastatic colon cancer in cytostatic treatment is around 24 months. However, a small subset of patients may present prolonged survivals of 5 to 10 years after diagnosis, revealing heterogeneity of tumor behavior and response to treatment. Our clinical case represents a long survivor patient despite the advanced stage of his oncological mucinous-colorrectal disease, endorsed in the scientific literature as having worse rates of objective response and less survival. There are different therapeutic approaches that can achieve a significant overall survival. It is essential in clinical practice to use all drugs available to achieve increase of progression-free survival and overall survival, with maintenance of an adequate quality of life.
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References
1. Van Cutsem E, Cervantes A, Adam R, et al. ESMO consensus guidelines for the Management of Patients with Metastatic Colorectal Cancer. Ann Oncol 2016;27:1386-422.
2 Dy GK, Hobday TJ, Nelson G, et al. Long-term survivors of metastatic colorectal cancer treated with systemic chemotherapy alone: A North Central Cancer Treatment Group Review of 3811 Patients, N0144. Clin Colorectal Cancer 2009;8(2):88-93.
3. Soerjomataram I, Thong MS, Ezzati M, et al. Colorectal cancer survivors live a large proportion of their remaining life in good health. Cancer Causes Control 2012;23:1421-8.
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Illán A, Aires J, Quintana L. Long survival in a patient with metastatic colorrectal carcinoma: reality or utopia? . 4817/2016


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Publication history

Received: 29/12/2016

Accepted: 16/02/2017

Online First: 10/07/2017

Published: 31/08/2017

Article Online First time: 193 days

Article editing time: 245 days


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