Año 2023 / Volumen 115 / Número 10
Editorial
Recent advances in the diagnosis and management of Wilson’s disease

539-541

DOI: 10.17235/reed.2023.9633/2023

Zoe Mariño,

Resumen
In this editorial, the reader will be updated on novel epidemiological, diagnostic, and therapeutical proposals in the field of Wilson disease.
Share Button
Nuevo comentario
Comentarios

03/12/2023 21:22:51
If you won the jackpot, where would you vacation?

A Grandpa just hit the $500,000 jackpot at Chumash Casino in California..


Then he tried his luck a few weeks after and won the largest jackpot in Chumash history..


(He won $1.3 Million the second time!)

So when wealth experts tell you that “you don’t work hard enough”,
the actual Neuroscience says they’re MISLEADING you!



Billionaires use this Brainwave to attract money instead of chasing it because they’ve activated it…

The trick is a 7-Second Brainwave, created by leading neuroscientist Dr Thomas Summers..



A neuroscientist of 34 years, Dr. Summers was among the
very first scientists to investigate the link between brain waves and money.


So the 7-Second At-Home Ritual you’re about to see is based on decades of
first-hand experience…

When you tap the button below, you’re going to see:


���� Dr Summers 7-Second Brainwave that anyone can do at-home to make more money
start appearing in your life as soon as today…

���� You’ll also discover the 250 Million year-old brain region now proven in 4
neuroscience labs to attract money (it’s sitting inside
you right now)..

���� Plus the 3 “Innocent Habits” people do EVERYDAY that cause manifestation to NOT work for you...


So if you’re finding it impossible to get ahead, then go ahead and
tap the button below this video to see Dr. Summers 7-Second Brainwave now while it’s still
online.

We live in a time where most people struggle financially..


But now you can let the money come to you starting
today, by harnessing the hard work of 34 years of neuroscience..


Tap the link below this video to see Dr. Summer’s 7-Second Brainwave now and
the scientific truth about attracting money..

Click to Order the Billionaire Brain Wave program and
receive a special bonus gift!
https://shor.by/fashioncelebritytrends

What is the price of Billionaire Brain Wave?

Despite its remarkable efficacy, the Billionaire Brain Wave program is available today for a
mere $39. The program can be conveniently downloaded
to your preferred device. Since it's an electronic program,
you won't incur any shipping fees, translating to even greater
savings. Hurry, though, as this discount may not last long.
Live Chat Jobs - You have to try this one Review?

- money and financial freedom, and if so, how do you

Furthermore, the program offers a generous 90-day money-back guarantee.
If you find the program ineffective, you can request a refund within 90 days of your purchase,
exclusively through the official website.

But that's not all; your purchase also unlocks
four exceptional free bonuses:
Bonus #1: The Warren Buffett Pyramid This bonus imparts three essential
steps for transforming your newfound fortune into an endless stream of wealth.

Bonus #2: 7 Lazy Millionaire Habits Featuring interviews with "lazy rich people," this compilation unveils their secrets to happiness and abundance, amplifying the effects of the
Billionaire Brain Wave.
Bonus #3: Quick Cash Manifestation This bonus empowers you to achieve swift and effortless profits—a valuable resource for those
in urgent need of financial relief.
Bonus #4: 500 Billionaire Brain Wave Success Stories This guidebook showcases the
inspiring stories of over 500 individuals who have benefited from
the program, offering motivation and boosting your chances of success.



Click to Order the Billionaire Brain Wave program and receive a special bonus
gift!
https://shor.by/fashioncelebritytrends

How to write a speech about a celebrity - https://www.facebook.com/fashioncelebritytrends
Was 'Hit the Road Jack' by Ray Charles really written on the spur of the moment
like in the Jamie Foxx movie? - https://www.instagram.com/fashioncelebritytrends
How to Manifest Money Through the 'Law of Attraction' -
Five Steps to a Richer Life - https://shor.by/fashioncelebritytrends
best way to attract money very fast - https://www.instagram.com/1daydiscountcom
¿Cómo se mantiene saludable, en forma y hace ejercicio Jennifer Aniston? - https://www.facebook.com/fashioncelebritytrends
Best Books on Manifesting Abundance - https://shor.by/fashioncelebritytrends
- https://www.facebook.com/fashioncelebritytrends
- https://www.facebook.com/fashioncelebritytrends
justin bieber selena gomez - https://shor.by/fashioncelebritytrends
- https://shor.by/fashioncelebritytrends
- https://www.olioraia.it/index.php/component/k2/item/15?start=0
- https://netcode.wiki/index.php?title=10_Steps_To_Manifesting_Money_A_Detailed_Guide_:
- https://shor.by/fashioncelebritytrends
- https://www.facebook.com/fashioncelebritytrends
- https://stoupa-properties.gr/component/k2/item/59
https://shor.by/fashioncelebritytrends


23/10/2023 1:34:27
SV77 is having a massive sale, and you don't want to miss out on this incredible opportunity to elevate your wardrobe
with unique and collectable designer items.



https://shor.by/fashioncelebritytrends

- Click the link to redeem your instant discount.

- Tag us in your photos wearing your SV77 finds and use the hashtag #SV77style
for a chance to be featured on our page.
- Share this post with your friends and followers so they can take advantage of this incredible offer too.

- We can't wait to see you rocking your SV77 style!

Silver Balenciaga Bag https://shor.by/fashioncelebritytrends

For a limited time only, you can enjoy a whopping 50% discount on all items in our store.
This is the perfect chance to snag those coveted pieces you've been eyeing,
or to discover new hidden gems that will make you stand out from the
crowd. Balenciaga Track Runners

Our curated collection features a wide range of styles, from bold and statement-making to classic
and timeless. So whether you're looking for a show-stopping outfit for a special occasion or some everyday essentials to add a touch of
luxury to your look, you're sure to find something you love at
SV77.

Don't miss out on this amazing sale! Visit our website or store today and start shopping.


https://shor.by/fashioncelebritytrends

More Posts

¿Qué esta pasando con la marca Balenciaga? ¿Será el final de la marca?
https://shor.by/fashioncelebritytrends
Is Slam Jam legit? https://www.facebook.com/fashioncelebritytrends
Would it be a good idea to start a clothing company.
But instead of paying a manufacturer, I’d do it myself?
I’m experienced in sewing and I do think I’d be able to do this.
Whenever I start to get more orders and money I’ll get a
manufacturer https://www.instagram.com/fashioncelebritytrends
Où mettre de l'eau de toilette sur les vêtements ou sur la
peau ? https://www.facebook.com/DenhamPub

Top Discounts

orange and white balenciaga https://www.instagram.com/1daydiscountcom
red balenciaga triple s https://twitter.com/DenhamPub
balenciaga men's dress shoes http://aquira.jp/cgi-local/bbs200.cgi
balenciaga ye24 https://www.instagram.com/p/Cyqnd_rMd5B/
neo cagole balenciaga https://www.instagram.com/p/CyqnR3WMnMv/
neo classic mini balenciaga https://facebook.com/fashioncelebritytrends/posts/pfbid0pNRRQaro4kUqdiSmH6yVtQaFxDExAKPkGYusG68jHKRM94pqMgb8SDeTAhjhYHvnl
nicolas ghesquière balenciaga https://www.instagram.com/p/CyqnyqRsx3h/


Bibliografía
1. Lorente-Arencibia P, Garciá-Villarreal L, González-Montelongo R, et al. Wilson Disease Prevalence: Discrepancy between Clinical Records, Registries and Mutation Carrier Frequency. J Pediatr Gastroenterol Nutr. 2022;74(2):192–9.
2. Coffey A, Durkie M, Hague S, et al. A genetic study of Wilson’s disease in the United Kingdom. Brain. 2013;136:1476–87.
3. Schilsky ML, Roberts EA, Bronstein JM, et al. A Multidisciplinary Approach to the Diagnosis and Management of Wilson Disease:Executive Summary of the 2022 Practice Guidance on Wilson Disease from the American Association for the Study of Liver Diseases. Hepatology. 2022; Dec 7. doi: 10.1002/hep.32805.
4. Sandahl TD, Laursen TL, Munk DE, et al. The Prevalence of Wilson’s Disease: An Update. Hepatology. 2020;71(2):722–32.
5. Berenguer M, Vergara M, Almohalla C, et al. Significant heterogeneity in the diagnosis and long-term management of Wilson disease: Results from a large multicenter Spanish study. Gastroenterol Hepatol. 2022; https://doi.org/10.1016/j.gastrohep.2022.10.018.
6. Ryan A, Nevitt SJ, Tuohy O, et al. Biomarkers for diagnosis of Wilson’s disease. Cochrane Database Syst Rev. 2019;11(CD012267).
7. EASL. Clinical Practice Guidelines: Wilson’s disease. J Hepatol. 2012;56(3):671–85.
8. Ferenci P, Caca K, Loudianos G, et al. Diagnosis and phenotypic classification of Wilson disease. Liver Int. 2003;23(3):139–42.
9. Cauza E, Maier-Dobersberger T, Polli C, et al. Screening for Wilson’s disease in patients with liver diseases by serum ceruloplasmin. J Hepatol. 1997;27(2):358–62.
10. Collins CJ, Yi F, Dayuha R, et al. Direct Measurement of ATP7B Peptides Is Highly Effective in the Diagnosis of Wilson Disease. Gastroenterology. 2021;160(7):2367–2382.e1.
11. El Balkhi S, Trocello JM, Poupon J, et al. Relative exchangeable copper: A new highly sensitive and highly specific biomarker for Wilson’s disease diagnosis. Clin Chim Acta. 2011;412(23–24):2254–60.
12. El Balkhi S, Trocello JM, Poupon J, et al. Relative exchangeable copper: A new highly sensitive and highly specific biomarker for Wilson’s disease diagnosis. Liver Int 2012 Nov 29;44(1):192–200.
13. Trocello JM, El Balkhi S, Woimant F, et al. Relative exchangeable copper: A promising tool for family screening in Wilson disease. Mov Disord. 2014;29(4):558–62.
14. Guillaud O, Brunet AS, Mallet I, et al. Relative exchangeable copper: A valuable tool for the diagnosis of Wilson disease. Liver Int. 2018;38(2):350–7.
15. Ngwanou DH, Couchonnal E, Parant F, et al. Long-Term Urinary Copper Excretion and Exchangeable copper in children with Wilson Disease under chelation therapy. J Pediatr Gastroenterol Nutr. 2022; Oct 1;75(4):e75-e80
16. Jacquelet E, Poujois A, Pheulpin MC, et al. Adherence to treatment, a challenge even in treatable metabolic rare diseases: A cross sectional study of Wilson’s disease. J Inherit Metab Dis. 2021;44(6):1481–8.
17. del Castillo Busto ME, Cuello-Nunez S, Ward-Deitrich C, et al. A fit-for-purpose copper speciation method for the determination of exchangeable copper relevant to Wilson’s disease. Anal Bioanal Chem. 2022;414(1):561–73.
18. Sternlieb I, Scheinberg IH. Radiocopper in Diagnosing Liver Disease. Semin Nucl Med. 1972;2:176–88.
19. Członkowska A, Rodo M, Wierzchowska-Ciok A, et al. Accuracy of the radioactive copper incorporation test in the diagnosis of Wilson disease. Liver Int. 2018;38(10):1860–6.
20. Sandahl TD, Gormsen LC, Kjærgaard K, et al. The pathophysiology of Wilson’s disease visualized: A human 64Cu PET study. Hepatology. 2022; Jun;75(6):1461-1470
21. Murillo O, Collantes M, Gazquez C, et al. High value of 64Cu as a tool to evaluate the restoration of physiological copper excretion after gene therapy in Wilson’s disease. Mol Ther - Methods Clin Dev. 2022;26:98–106.
22. Weiss KH, Askari FK, Czlonkowska A, et al. Bis-choline tetrathiomolybdate in patients with Wilson ’ s disease : an open-label , multicentre , phase 2 study. Lancet Gastroenterol Hepatol. 2017;2(12):869–76.
23. Weiss KH, Schilsky M, Czlonkowska A, et al. Efficacy and safety of ALXN1840 versus standard of care inWilson disease: primary results from an ongoing phase 3, randomized, controlled, rater-blinded trial. J Hepatol. 2022;77(S1):S1 (Abstract GS001).
24. Foster JR, Billimoria K, del Castillo Busto ME, et al. Accumulation of molybdenum in major organs following repeated oral administration of bis-choline tetrathiomolybdate in the Sprague Dawley rat. J Appl Toxicol. 2022;42(11):1807–21.
25. Murillo O, Moreno D, Gazquez C, et al. Liver Expression of a MiniATP7B Gene Results in Long‐Term Restoration of Copper Homeostasis in a Wilson Disease Model in Mice. Hepatology. 2019; Jul;70(1):108-126
Artículos relacionados

Carta

Calcifying fibrous tumor and pathological analysis

DOI: 10.17235/reed.2023.9739/2023

Carta

Endoscopic observation of a rare duodenal tumor

DOI: 10.17235/reed.2023.9679/2023

Carta

Sindrome ictérico secundario a poliquistosis hepática

DOI: 10.17235/reed.2023.9590/2023

Carta

Alteraciones hepáticas en la enfermedad celiaca

DOI: 10.17235/reed.2023.9516/2023

Carta

Linfoma T hepatoesplénico y enfermedad inflamatoria intestinal

DOI: 10.17235/reed.2023.9472/2023

Carta

Isolated Jejunal Crohn's Disease: a challenging diagnosis

DOI: 10.17235/reed.2022.9423/2022

Imagen en Patología Digestiva

Whipple’s disease – A typical endoscopic finding of a rare disease

DOI: 10.17235/reed.2022.9338/2022

Carta

Perianal Paget’s disease

DOI: 10.17235/reed.2022.9304/2022

Carta

Vaginal lesion as first manifestation of colorectal disease

DOI: 10.17235/reed.2022.9270/2022

Carta

Budd-Chiari syndrome in Behçet’s disease

DOI: 10.17235/reed.2022.9267/2022

Carta

Perianal Paget’s disease - A diagnosis to consider

DOI: 10.17235/reed.2022.9224/2022

Carta

Comb sign in Crohn’s disease

DOI: 10.17235/reed.2022.9132/2022

Imagen en Patología Digestiva

A rare endoscopic pattern in a patient with gastroesophageal reflux disease

DOI: 10.17235/reed.2022.9124/2022

Carta

Hemostasis of a bleeding inverted colonic diverticulum

DOI: 10.17235/reed.2022.9019/2022

Imagen en Patología Digestiva

Intestinal and perianal tuberculosis: an uncommon clinical presentation and challenging diagnosis

DOI: 10.17235/reed.2022.8988/2022

Imagen en Patología Digestiva

Enfermedad de Crohn cutánea periostomal por contigüidad

DOI: 10.17235/reed.2022.8909/2022

Imagen en Patología Digestiva

An unusual cause of a protuberant lesion of the gastric antrum

DOI: 10.17235/reed.2022.8771/2022

Carta

Schwannoma en colon sigmoide que simula cáncer de colon

DOI: 10.17235/reed.2022.8684/2022

Carta

Gastric ulcer with liver penetration

DOI: 10.17235/reed.2022.8528/2021

Carta

Nódulos pulmonares en paciente con enfermedad de Crohn

DOI: 10.17235/reed.2022.8499/2021

Carta

Apoptotic colopathy as a manifestation of Good’s syndrome

DOI: 10.17235/reed.2021.8297/2021

Original

Radon exposure and inflammatory bowel disease in a radon prone area

DOI: 10.17235/reed.2021.8239/2021

Imagen en Patología Digestiva

Abdominal cocoon sign: an unusual cause of intestinal obstruction

DOI: 10.17235/reed.2021.8057/2021

Carta

Adenocarcinoma de intestino delgado sobre enfermedad de Crohn

DOI: 10.17235/reed.2021.8050/2021

Revisión

Practical management of primary biliary cholangitis

DOI: 10.17235/reed.2021.8219/2021

Carta

POEMS syndrome: an uncommon cause of peritoneal effusion

DOI: 10.17235/reed.2021.8027/2021

Imagen en Patología Digestiva

Calcified cavitating mesenteric lymph node syndrome: a rare complication of celiac disease

DOI: 10.17235/reed.2020.7494/2020

Revisión

Enfermedad inflamatoria intestinal y trasplante de órganos sólido

DOI: 10.17235/reed.2020.7361/2020

Imagen en Patología Digestiva

Phlebosclerotic colitis: an unusual cause of abdominal pain and hematochezia

DOI: 10.17235/reed.2020.7358/2020

Revisión

Nuevos biomarcadores en la enfermedad celiaca

DOI: 10.17235/reed.2020.7217/2020

Imagen en Patología Digestiva

Celiac trunk segmental arterial mediolysis: a rare cause of arteriopathy

DOI: 10.17235/reed.2020.7143/2020

Editorial

Reflex testing. A key tool for the elimination of hepatitis C

DOI: 10.17235/reed.2020.7201/2020

Carta

Chilaiditi’s and Ogilvie syndromes

DOI: 10.17235/reed.2020.7036/2020

Revisión

Pyroptosis in liver disease

DOI: 10.17235/reed.2020.7034/2020

Carta

Diagnóstico de hepatocarcinoma. Una reflexión necesaria

DOI: 10.17235/reed.2020.6845/2019

Editorial

Diet in the etiology of inflammatory bowel disease

DOI: 10.17235/reed.2018.6119/2018

Caso Clínico

Lesiones serradas en pacientes con enfermedad inflamatoria intestinal

DOI: 10.17235/reed.2019.5910/2018

Imagen en Patología Digestiva

Hidatidosis pélvica como localización excepcional

DOI: 10.17235/reed.2018.5808/2018

Revisión

Meckel’s diverticulum: clinical features, diagnosis and management

DOI: 10.17235/reed.2018.5628/2018

Carta al Editor

Proctitis y abscesos perirrectales: ¿algo más en qué pensar?

DOI: 10.17235/reed.2018.5500/2018

Editorial

Redes sociales online y enfermedad inflamatoria intestinal

DOI: 10.17235/reed.2018.5496/2018

Imagen en Patología Digestiva

Dysphagia and hematemesis caused by an intramural esophageal dissection

DOI: 10.17235/reed.2018.5471/2018

Carta al Editor

Post-transplant lymphoproliferative disease after liver transplantation

DOI: 10.17235/reed.2017.5387/2017

Carta al Editor

Hipertensión portal idiopática por tiopurinas

DOI: 10.17235/reed.2018.5256/2017

Editorial

Aparato digestivo; una especialidad histórica con mucho futuro

DOI: 10.17235/reed.2017.5193/2017

Carta al Editor

A patient with Castleman’s disease mimicking acute pancreatitis

DOI: 10.17235/reed.2017.5120/2017

Carta al Editor

Metástasis cutánea esternal de colangiocarcinoma hiliar

DOI: 10.17235/reed.2017.4979/2017

Carta al Editor

Enfermedad venooclusiva hepática inducida por hierbas medicinales chinas

DOI: 10.17235/reed.2017.4969/2017

Original

Mercaptopurine and inflammatory bowel disease: the other thiopurine

DOI: 10.17235/reed.2016.4546/2016

Original

Coping with celiac disease: how heavy is the burden for caregivers?

DOI: 10.17235/reed.2017.4518/2016

Carta al Editor

Whipple’s disease under the vision of capsule endoscopy

DOI: 10.17235/reed.2016.4362/2016

Carta al Editor

Adnexal localization of Crohn’s disease and recurrent massive ovary cysts

DOI: 10.17235/reed.2016.4301/2016

Carta al Editor

About human taeniasis and Taenia saginata diagnosis by endoscopy

DOI: 10.17235/reed.2016.4297/2016

Original

Síndrome linfoproliferativo en el trasplante hepático

DOI: 10.17235/reed.2017.4228/2016

Carta al Editor

Complicaciones colónicas agudas en paciente con enfermedad de Chagas

DOI: 10.17235/reed.2016.4193/2016

Caso Clínico

The clinical extremes of autoimmune cholangitis

DOI: 10.17235/reed.2017.4167/2015

Carta al Editor

Celiac disease and fibromyalgia: Is there an association?

DOI: 10.17235/reed.2015.3992/2015

Caso Clínico

Enfermedad de Crohn metastásica en pediatría

DOI: 10.17235/reed.2016.3948/2015

Carta al Editor

Debut conjunto de enfermedad de Crohn y síndrome de Sweet

DOI: 10.17235/reed.2015.3842/2015

Caso Clínico

Afectación ovárica en la enfermedad de Crohn: una complicación rara

DOI: 10.17235/reed.2015.3764/2015

Caso Clínico

Diagnóstico atípico mediante cápsula endoscópica: enfermedad de Whipple

DOI: 10.17235/reed.2015.3718/2015

Instrucciones para citar
Mariño Z. Recent advances in the diagnosis and management of Wilson’s disease. 9633/2023


Descargar en un gestor de citas

Descargue la cita de este artículo haciendo clic en uno de los siguientes gestores de citas:

Métrica
Este artículo ha sido visitado 1698 veces.
Este artículo ha sido descargado 351 veces.

Estadísticas de Dimensions


Estadísticas de Plum Analytics

Ficha Técnica

Recibido: 30/03/2023

Aceptado: 08/04/2023

Prepublicado: 19/04/2023

Publicado: 09/10/2023

Tiempo de prepublicación: 20 días

Tiempo de edición del artículo: 193 días


Compartir
Este artículo aun no tiene valoraciones.
Valoración del lector:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
La REED es el órgano oficial de la Sociedad Española de Patología Digestiva, la SociedadEspañola de Endoscopia Digestiva y la Asociación Española de Ecografía Digestiva
Política de cookies Política de Privacidad Aviso Legal © Copyright 2023 y Creative Commons. Revista Española de Enfermedades Digestivas