Year 2022 / Volume 114 / Number 8
Letter
A rare case of monomorphic epitheliotropic intestinal T-cell lymphoma mimicking Crohn’s disease

497-498

DOI: 10.17235/reed.2022.8757/2022

Joel Ferreira Silva, Renato Medas, Elsa Fonseca, Guilherme Macedo,

Abstract
A 70-years-old male was referred to us due to bloody diarrhea and involuntary weight loss during the last 2 months. Laboratory workup revealed anemia, hypoalbuminemia, and elevated reactive-C-protein. Computed tomography documented a wall thickening of sigmoid colon. Colonoscopy revealed pleomorphic ulceration of the sigmoid and descending colon. Aphthous ulcers were seen in ilium. Histology revealed mucosal infiltration with small sized atypical lymphoid cells in the epithelium and lamina propria, with extensive epitheliotropism.
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References
1. Yi JH, Lee GW, Do YR, et al. Multicenter retrospective analysis of the clinicopathologic features of monomorphic epitheliotropic intestinal T-cell lymphoma. Ann Hematol 2019;98:2541-2550.
2. Tan SY, Ooi AS, Ang MK, et al. Nuclear expression of MATK is a novel marker of type II enteropathy-associated T-cell lymphoma. Leukemia 2011;25:555-7.
3. Swerdlow SH CE, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW (2017) WHO classification of tumours of haematopoietic and lymphoid tissues. WHO Classification of Tumours, Revised 4th Edition, Volume 2
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Silva J, Medas R, Fonseca E, Macedo G. A rare case of monomorphic epitheliotropic intestinal T-cell lymphoma mimicking Crohn’s disease. 8757/2022


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Publication history

Received: 27/02/2022

Accepted: 01/03/2022

Online First: 08/03/2022

Published: 27/07/2022

Article Online First time: 9 days

Article editing time: 150 days


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