Year 2023 / Volume 115 / Number 7
Letter
Non-invasive liver fibrosis assessment: is transient elastography mandatory?

394-395

DOI: 10.17235/reed.2022.9214/2022

Maria Azevedo Silva, Carina Leal, André Ruge Gonçalves, Catarina Atalaia Martins, Pedro Russo, Alexandra Fernandes, Antonieta Santos, Isabel Cotrim,

Abstract
Real-time elastography (RTE) is a conventional ultrasonography-based liver stiffness assessment technique developed in chronic viral hepatitis. Evidence of its applicability in other aetiologies is lacking. This study aims to determine RTE diagnostic accuracy for advanced fibrosis in compensated chronic liver disease (cCLD) and to compare it with the biochemical scores FIB-4 and APRI, using transient elastography (TE) as the gold standard. A single center cross-sectional study including cCLD patients was conducted. RTE with assessment of Liver Fibrosis Index and TE were performed in the same day by different operators blind to the other technique result. The scores FIB-4 and APRI were calculated. Fibrosis cut-off values were inferred from previous evidence.
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References
1. Ge L, Shi B, Song Y, et al. Clinical value of real-time elastography quantitative parameters in evaluating the stage of liver fibrosis and cirrhosis. Exp Ther Med 2015;10:983–90.
2. Kobayashi K, Nakao H, Nishiyama T, et al. Diagnostic Accuracy of Real-Time Tissue Elastography for the Staging of Liver Fibrosis: A Meta-Analysis. Eur Radiol 2015;25:230–8.
3. Berzigotti A, Tsochatzis E, Boursier J, et al. EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis – 2021 update. J Hepatol 2021;75:659–89.
4. Cast́era L, Foucher J, Bernard PH, et al. Pitfalls of liver stiffness measurement: A 5-year prospective study of 13,369 examinations. Hepatology 2010;51:828–35.
5. Kim YW, Kwon JH, Jang JW, et al. Diagnostic usefulness of real-time elastography for liver fibrosis in chronic viral hepatitis B and C. Gastroenterol Res Pract 2014;1:1–7.
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Citation tools
Azevedo Silva M, Leal C, Gonçalves A, Martins C, Russo P, Fernandes A, et all. Non-invasive liver fibrosis assessment: is transient elastography mandatory?. 9214/2022


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Publication history

Received: 18/09/2022

Accepted: 21/09/2022

Online First: 30/09/2022

Published: 06/07/2023

Article Online First time: 12 days

Article editing time: 291 days


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