Year 2016 / Volume 108 / Number 4
Letter to the Editor
Ulcerative colitis in a patient with common variable immunodeficiency: does the treatment differ from the routine?

235-236

DOI: 10.17235/reed.2016.4115/2015

Carlos Alventosa Mateu, Lucía Ruiz Sánchez, Cirilo Amorós García,

Abstract
Common variable immunodeficiency (CVID) is associated with gastrointestinal manifestations, in particular diarrhea (1,2). It is linked to autoimmune disorders such as nodular lymphoid hyperplasia (NLH), possibly increasing the risk of lymphoma (3). The prevalence of chronic inflammatory bowel disease (CIBD) in these patients is increased, above all Crohn's disease (4,5) and its treatment does not seem to differ from the standard (2). We were presented with a patient with CVID and ulcerative colitis treated in the conventional manner.
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References
1. Agarwal S, Smereka P, Harpaz N, et al. Characterization of immunologic defects in patients with common variable immunodeficiency (CVID) with intestinal disease. Inflamm Bowel Dis. 2011; 17:251-9.
2. Agarwal S, Mayer L. Diagnosis and treatment of gastrointestinal disorders in patients with primary immunodeficiency. Clin Gastroenterol Hepatol 2013; 11:1050-63.
3. Said-Criado I, Gil-Aguado A. Nodular lymphoid hyperplasia in common variable immunodeficiency. Lancet 2014; 383: e2.
7. Vázquez-Morón JM, Pallarés-Manrique H, Martín-Suárez IJ, et al. Enfermedad de Crohn-like en un paciente con inmunodeficiencia común variable tratada con azatioprina y adalimumab. Rev Esp Enferm Dig 2013; 105: 299-302.
9. Nos P, Bastida G, Beltran B, et al. Crohn’s disease in common variable immunodeficiency: treatment with antitumor necrosis factor alpha. Am J Gastroenterol 2006; 101: 2165-6.
10. Borba de Arruda SM, do Rego Silva AM, Cezário de Barros KS, et al. Ulcerative colitis and common variable immunodeficiency: case report. Inflamm Bowel Dis 2009; 15:478-81.
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Alventosa Mateu C, Ruiz Sánchez L, Amorós García C. Ulcerative colitis in a patient with common variable immunodeficiency: does the treatment differ from the routine? . 4115/2015


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Publication history

Received: 19/11/2015

Accepted: 14/12/2015

Online First: 25/02/2016

Published: 01/04/2016

Article revision time: 17 days

Article Online First time: 98 days

Article editing time: 134 days


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