Year 2013 / Volume 105 / Number 3
Editorial
Rationalizing the use of PPIs: An unresolved matter

pp. 121-124

Julio Ponce y Juan V. Esplugues

Abstract
The abnormally high use of proton-pump inhibitors (PPIs) has been repeatedly denounced for many years (1), and attention has been drawn towards the economic burden it represents (2,3). Multiple scientific publications have reported this problem in many countries. In the present issue of the Journal an observational, prospective study based on a survey to analyze the inappropriate (not recommended by clinical guidelines) indication of chronic PPI use (daily for over one year) in outpatients seen at a specialty hospital in Mexico is reported (4). The authors find an overall rate of inappropriateness of 35.3 %, a figure within the lower range of those reported, which exceed 60 % in many countries including Australia (5,6), United Kingdom (7), and Greece (8), and in four studies performed in Spain (9,10-12). All these studies discuss oral therapy with PPIs, but inappropriateness is also very high (above 75 %) in terms of dosage and length of intravenous therapy (13).
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01/06/2013 11:39:22
Enhorabuena a los autores por este editorial. En una época de grave crisis económica, iniciativas de racionalización del gasto sanitario basadas en la evidencia científica y estudios de coste/beneficio deben ser sin duda potenciadas.


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