Year 2026 / Volume 118 / Number 1
Review
Novel insights into carbohydrate-to-fiber ratio and constipation: NHANES findings suggest a turning point

28-40

DOI: 10.17235/reed.2024.10306/2024

Yin Chen, Meisheng Ding,

Abstract
Background: Constipation, a widespread global issue, prompted an investigation into the intricate relationship between dietary factors and this condition. This study delves into the association between carbohydrate-to-fiber (CF) ratio and constipation, employing data from the National Health and Nutrition Examination Survey (NHANES) and a comprehensive meta-analysis. Methods: Utilizing NHANES data (2005-2010) from 7752 adults, constipation was defined based on stool type (Bristol Stool Form Scale types 1 or 2). The CF ratio was calculated, revealing an L-shaped, non-linear association with constipation. A meta-analysis of 16 studies (1626 participants) confirmed a positive effect of dietary fiber on constipation, emphasizing the robustness of the findings. Results: Among participants, constipation prevalence stood at 13.98%. The CF ratio exhibited a turning point at 26.92/day, with adjusted odds ratios for constipation indicating a decrease with higher CF ratios. Meta-analysis results supported these findings, demonstrating a significant positive effect of dietary fiber on constipation. Conclusion: This study illuminates a nuanced relationship between CF ratio and constipation, suggesting a critical turning point at 26.92/day. These findings underscore the importance of dietary assessment, offering valuable insights for clinicians and individuals. Further prospective research is warranted to validate the CF ratio as a robust dietary assessment tool.
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Chen Y, Ding M. Novel insights into carbohydrate-to-fiber ratio and constipation: NHANES findings suggest a turning point. 10306/2024


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Publication history

Received: 28/01/2024

Accepted: 05/12/2024

Online First: 09/01/2025

Published: 14/01/2026

Article revision time: 200 days

Article Online First time: 347 days

Article editing time: 717 days


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