Year 2016 / Volume 108 / Number 5
Letter to the Editor
Lupus as a paraneoplastic manifestation of cholangiocarcinoma

292

DOI: 10.17235/reed.2016.4064/2015

Yolanda González Amores, Sofía Hernando Rebollar, Aida Casado Bernabeu,

Abstract
Tumors originating in the digestive system, like those in other areas, whether solid or otherwise, may present with extradigestive manifestations in the setting of a paraneoplastic syndrome. Systemic lupus erythematosus (SLE) is an autoimmune condition most commonly involving women of childbearing age. On occasion it represents a paraneoplastic manifestation heralding a primary tumor. Cancer suspicion is therefore a key element for newly diagnosed SLE cases with nonstandard epidemiology even in the absence of suggestive symptoms, and digestive tumors should be included in the differential diagnosis.
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References
Hidalgo-Conde A, de Haro Liger M, Abarca-Costalago M, et al. Incidence of cáncer in a cohort of Spanish patients with systemic lupus erythematosus. Reumatol Clin. 2013: 9:359-64.
Masselli G, Gualdi G. Hilar cholangiocarcinoma: MRI/MRCP in staging and treatment planning. Abdom Imaging. 2008;33:444-51.
Jenkins D, McPherson T. Paraneoplastic subacute cutaneous lupus erythematosus associated with cholangiocarcinoma. Australas J Dermatol. 2014 Nov 4.
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González Amores Y, Hernando Rebollar S, Casado Bernabeu A. Lupus as a paraneoplastic manifestation of cholangiocarcinoma. 4064/2015


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Publication history

Received: 22/10/2015

Accepted: 09/12/2015

Online First: 29/02/2016

Published: 29/04/2016

Article Online First time: 130 days

Article editing time: 190 days


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