Year 2016 / Volume 108 / Number 8
Case Report
Immmunodeficiencies and autoimmune diseases: common variable immunodeficiency and Crohn-like

520-523

DOI: 10.17235/reed.2015.3872/2015

Cristina Saldaña Dueñas, Saioa Rubio Iturria,

Abstract
Common variable immunodeficiency (CVI) gives a major risk of principally respiratory and digestive infections. It is associated with autoimmune diseases, granulomatous process and neoplasias. The digestive clinic is common, in 10% of patients it is the only symptom, and 60 % present chronic diarrhea. Clinically it can be confused and related with other pathologies such as inflammatory bowel disease which is infrequent (2-13%). We present the case of a patient with CVI with digestive symptoms being diagnosed of Crohn-like disease with extent ileal affectation. The main treatment of these patients is the same as classical Crohn disease although in the most severe cases, as this one, the use of immunosupresors is necessary. At this time the patient remains on clinical remmision with infliximab. She presented a previous adverse reaction with adalimumab. The few case series in this pathology makes the treatment with immunomodulators in this immunodeficiency a real diagnostic and therapeutic challenge.
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References
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Saldaña Dueñas C, Rubio Iturria S. Immmunodeficiencies and autoimmune diseases: common variable immunodeficiency and Crohn-like. 3872/2015


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Publication history

Received: 29/05/2015

Accepted: 22/06/2015

Online First: 15/12/2015

Published: 29/07/2016

Article revision time: 17 days

Article Online First time: 200 days

Article editing time: 427 days


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