Year 2013 / Volume 105 / Number 3
Original
Inadequate prescription of chronic consumption of proton pump inhibitors in a hospital in Mexico. Cross-sectional study

pp. 131-137

Jaime Alberto Sánchez Cuén, Ana Bertha Irineo Cabrales, Gregorio Bernal Magaña y Felipe de Jesús Peraza Garay

Abstract
Introduction: PPIs have been an enormous therapeutic advance in acid-related diseases. However, it has been detected an abuse in its consumption. The aim of this study was to determine the frequency of inadequate prescription of chronic use of PPIs in outpa- tients in a speciality hospital.

Material and methods: we performed a cross-sectional des- criptive study review. The study population were patients, chronic users of proton pump inhibitors (PPIs), attending outpatient consult in a hospital of government workers. We defined as chronic user of PPIs that patient that takes medication daily for over a year and inappropriate prescription, that one that has not been approved by the clinical guidelines. A simple random sampling was utilized. The following parameters were investigated: diagnosis and prescription of PPIs, time of use, at which level of care PPIs were prescribed (pri- mary care or specialist), self-medication, with or without endoscopy. For the statistical analysis, we used Student’s t-test and Chi-square, 95% confidence intervals and significance 0.05 %.

Results: we reviewed 153 patients, 40 (26.1 %) men and 113 (73.9 %) women, mean age 58 ± 11.4 years. The prescription of chronic treatment with PPIs was adequate in 64.7 % of patients and inadequate in 35.3 %. The most common appropriate prescription (31.3 %) of chronic use of PPIs was due to gastroesophageal reflux disease. The most common inadequate prescription was absence of diagnosis (22.2 %), polypharmacy without nonsteroidal antiin- flammatory drugs (16.6 %) and chronic gastritis (16.6 %). History of endoscopy were not statistically significant.

Conclusions: the frequency of inappropriate prescriptions of chronic use of PPIs was high, around 35.3 %, similar to those repor- ted in hospitals in developed countries.
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Jaime Alberto Sánchez Cuén, Ana Bertha Irineo Cabrales, Gregorio Bernal Magaña y Felipe de Jesús Peraza Garay. Inadequate prescription of chronic consumption of proton pump inhibitors in a hospital in Mexico. Cross-sectional study. 131-137


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