Year 2025 / Volume 117 / Number 5
Letter
Hyperbaric oxygen therapy for perianal Crohn’s disease

289-290

DOI: 10.17235/reed.2024.10378/2024

Akira Hokama,

Abstract
I read with great interest the letter by Calderón et al., who clearly described effectiveness of hyperbaric oxygen therapy (HBOT) for refractory ischemic ulcer at the ileorectal anastomosis in Crohn’s disease (CD). I congratulate them on their efforts in achieving a favorable long-term outcome. I would like to share my experience of HBOT for perianal CD (PCD). In addition, I discuss recent trials of HBOT for PCD.
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References
1. Calderón P, Quera R, Núñez P, et al. Treatment with hyperbaric oxygen in a Crohn’s disease patient. Rev Esp Enferm Dig 2024 Jan 18. doi: 10.17235/reed.2024.10166/2023.
2. Lansdorp CA, Buskens CJ, Gecse KB, et al. Hyperbaric oxygen therapy for the treatment of perianal fistulas in 20 patients with Crohn's disease: Results of the HOT-TOPIC trial after 1-year follow-up. United European Gastroenterol J 2022;10:160-8.
3. Catalán-Serra I, Ricanek P, Grimstad T. "Out of the box" new therapeutic strategies for Crohn´s disease: moving beyond biologics. Rev Esp Enferm Dig 2023;115:614-34. doi: 10.17235/reed.2022.9010/2022
4. Chen L, Wang Y, Zhou H, et al. The new insights of hyperbaric oxygen therapy: focus on inflammatory bowel disease. Precis Clin Med 2024;7:pbae001.
5. Chmelař D, Rozložník M, Hájek M, et al. Effect of hyperbaric oxygen on the growth and susceptibility of facultatively anaerobic bacteria and bacteria with oxidative metabolism to selected antibiotics. Folia Microbiol (Praha) 2024;69:101-8.
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Hokama A. Hyperbaric oxygen therapy for perianal Crohn’s disease. 10378/2024


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Publication history

Received: 01/03/2024

Accepted: 05/03/2024

Online First: 12/03/2024

Published: 08/05/2025

Article Online First time: 11 days

Article editing time: 433 days


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