Year 2013 / Volume 105 / Number 2
Letter to the Editor
Severe perianal disease degenerated to adenocarcinoma. Is close monitoring of long-term perianal disease necessary?

pp. 115-116-

Alfonso Alcalde Vargas, Claudio Trigo Salado, Eduardo Leo Carnerero, Francisco Javier Castell Monsalve, Olga Mateo Vico y José Luis Márquez Galán

Abstract
Although perianal fistulas are common in the natural history of Crohn’s disease (CD), accounting for around 30-50 % of cases, its malignant transformation is extremely rare, from 0.004 to 0.7 %.
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Alfonso Alcalde Vargas, Claudio Trigo Salado, Eduardo Leo Carnerero, Francisco Javier Castell Monsalve, Olga Mateo Vico y José Luis Márquez Galán. Severe perianal disease degenerated to adenocarcinoma. Is close monitoring of long-term perianal disease necessary?. 115-116-


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