Year 2016 / Volume 108 / Number 3
Original
Using autologous platelet-rich plasma for the treatment of complex fistulas

123-128

DOI: 10.17235/reed.2016.3946/2015

Almudena Moreno Serrano, Juan José García Díaz, Manuel Ferrer Márquez, Raquel Alarcón Rodríguez, Antonio Álvarez García, Ángel Reina Duarte,

Abstract
Objective: This study aims to demonstrate the effectiveness and safety of autologous fibrin gel rich in platelet growth factors for the treatment of complex perianal fistulas. Material and Methods: Prospective epidemiological study. Patients with complex perianal fistula or perianal fistula mere alteration of continence are included. identification of both holes and the journey, curettage of it and instillation of Vivostat PRF® in the way it is done to observe excess material by OFE. The variables analyzed were: age, sex, use of prior Seton clinic prevalent type of fistula, postoperative complications, fistula closure and impaired quality of life using the SF-36 test (v2). Results: From January 2011 to May 2013 have involved 23 patients, 12 men and 11 women, with an average age of 49 years and a minimum follow-up of 12 months. Two dropped out. 17 patients had low transsphincteric fistulas, 2 and 2 high transsphincteric intersphincteric with impaired continence. The most common symptom is the discharge. Twelve patients had a loose seton (62%), of which nine cured. Of all the patients we have operated the success rate is 62%. No patient developed incontinence after treatment. Only two reported a worse quality of life after surgery. Conclusion: This study demonstrates that there is a clear benefit to the use of Vivostat PRF® as a treatment for complex perianal fistulas. It is a highly reproducible technique with acceptable results and does not produce impairment of continence.
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Moreno Serrano A, García Díaz J, Ferrer Márquez M, Alarcón Rodríguez R, Álvarez García A, Reina Duarte Á, et all. Using autologous platelet-rich plasma for the treatment of complex fistulas . 3946/2015


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Publication history

Received: 26/07/2015

Accepted: 15/11/2015

Online First: 09/02/2016

Published: 26/02/2016

Article revision time: 101 days

Article Online First time: 198 days

Article editing time: 215 days


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