Year 2015 / Volume 107 / Number 9
Original
Characteristics and pattern of recurrence after curative surgery in oesophageal cancer

539-546

DOI: 10.17235/reed.2015.3748/2015

Elena Rodríguez-Camacho, Salvador Pita-Fernández, Sonia Pértega-Díaz, Beatriz López-Calviño, Teresa Seoane-Pillado,

Abstract
Background: Recurrence in oesophageal cancer continues to remain high after curative surgery. The aim of this study was to determine the presence of recurrence after curative surgery during follow-up, and the associated variables. Methods: A retrospective and prospective follow-up study in patients with an anatomical-pathological diagnosis of oesophageal cancer who underwent curative surgery (n=57) in the health district of XXX during the period 2003-2008. The calculation of recurrence-free survival was made using a competing risks survival analysis. Results: Out of the 57 patients included in the study, 87.7% were men with a mean age of 61.4±10.3 years. The median follow-up period was 18.5 months, during which 28 recurrences were detected (50.9%). Patients with dysphagia on diagnosis of the disease, as well as patients in stages III-IV, have a higher probability of recurrence during the follow-up period. The median disease-free interval was 8.5 months. After one year of follow up 57.1% of the recurrences were diagnosed, and 82.1% after 2 years of follow-up. The median post-recurrence survival rate was 4.7 months. After adjusting for a multivariate regression model, the variable with an independent effect for predicting recurrence is the TNM classification (HR=8.49). Conclusions: The majority of the recurrences will be developed during the 2 years after surgery, with a very poor prognosis. The predictor variable for recurrence is the TMN classification.
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References
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Rodríguez-Camacho E, Pita-Fernández S, Pértega-Díaz S, López-Calviño B, Seoane-Pillado T. Characteristics and pattern of recurrence after curative surgery in oesophageal cancer. 3748/2015


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Publication history

Received: 26/02/2015

Accepted: 03/05/2015

Online First: 11/06/2015

Published: 29/08/2015

Article revision time: 64 days

Article Online First time: 105 days

Article editing time: 184 days


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