Year 2015 / Volume 107 / Number 10
Letter to the Editor
Duodenal involvement by seminomatous tumors

640-641

DOI: 10.17235/reed.2015.3646/2014

Mario Rodriguez-Lopez, Rosalía Velasco-López, Sara Mambrilla-Herrero, Martin Bailon-Cuadrado, Katherine T. Plua, Luis M. Diez-González, Jose I. Blanco-Álvarez, Enrique Asensio-Díaz, Marta Gonzalo-Martín, Baltasar Pérez-Saborido, Jose L. Marcos-Rodríguez,

Abstract
Testicular germ cell tumors, though rare (1%), represent the most common neoplasm among young men. Gastrointestinal involvement from these malignancies usually presents as bowel obstruction and digestive bleeding, but their frequency is low (5%). The patterns of this involvement are: infiltration from affected retroperitoneal lymph nodes or, less frequently, by peritoneal seeding and direct hematogenous spread. Particularly, infiltration of duodenum is also rare, though its real frequency is not well defined. Moreover, the affinity for GI tract differs among the histological types of GCT, being seminomatous tumors an exceedingly unfrequent cause of duodenal infiltration. We herein present a recent case in our institution of severe anemia due to gastrointestinal bleeding in the context of giant retroperitoneal bulky metastatic mass infiltrating duodenum as first manifestation of a testicular pure seminoma.
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References
1. Sweetenham JW, Whitehouse JM, Williams CJ, et al. Involvement of the gastrointestinal tract by metastases from germ cell tumors of the testis. Cancer 1988;61:2566-70.
2. Johnson DE, Appelt G, Samuels ML, et al. Metastates from testicular carcinoma: Study of 78 autopsied cases. Urology 1976;8:234-9.
3. Chait MM, Kurtz RC, Hajdu SI. Gastrointestinal tract metastasis in patients with germ cell tumor of the testis. Am J Dig Dis 1978;23:925-8.
4. Fu S, Avezbakiyev B, Zhi W, et al. Germ cell cancer presenting as gastrointestinal bleeding and developing brain metastases: case report and review of the literature. Future Oncol 2012;8:1487-93.
5. Nord C, Fosa SD, Giercksky KE. Gastrointestinal presentation of germ cell malignancy. Eur Urol 2000;38:721-4.
6. Husband JE, Bellamy EA. Unusual thoracoabdominal sites of metastasis in testicular tumors. Am J Roentgenol 1985;145:1165-71.
7. Senadhi V, Dutta S. Testicular seminoma metastasis to the gastrointestinal tract and the necessity of surgery. J Gastrointest Cancer 2012;43:499-501.
8. Miocinovic R, Abaza R. Testicular seminoma presenting with duodenal perforation: A case report. J Med Case Rep 2008;2:294.
9. Fosado Gayosso M, Pérez Hernández JL, Bernal Sahagun F, et al. Upper gastrointestinal bleeding as an initial manifestation of metastasis, secondary to a choriocarcinoma in a patient suffering from testicular mixed germ cell tumour. Rev Esp Enferm Dig 2011;103:46-7.
10. Iglesias J, Lopez E, Macias F. Severe gastrointestinal bleeding secondary to duodenal metastasis from a choriocarcinoma. Rev Esp Enferm Dig 2009;101:720-2.
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Citation tools
Rodriguez-Lopez M, Velasco-López R, Mambrilla-Herrero S, Bailon-Cuadrado M, Plua K, Diez-González L, et all. Duodenal involvement by seminomatous tumors. 3646/2014


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Publication history

Received: 15/12/2014

Accepted: 05/02/2015

Online First: 14/07/2015

Published: 25/09/2015

Article revision time: 44 days

Article Online First time: 211 days

Article editing time: 284 days


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