Year 2020 / Volume 112 / Number 7
Letter
An acute episode of inflammatory bowel disease vs a rare manifestation of an Epstein-Barr virus-positive mucocutaneous ulcer. Case report

577-578

DOI: 10.17235/reed.2020.6737/2019

Ángel García-Romera, Selene González-Díaz, Laura Ramos,

Abstract
The Epstein-Barr virus-positive mucocutaneous ulcer is an entity that has been recently accepted in the literature, included under the lymphoproliferative disorders. Some publications provide information about a limited number of cases describing lesions that mainly involve the oropharynx and skin. However, its rapid onset in the colon, causing a perforation, has not been reported.
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Comments

11/07/2020 19:32:26
comentar :
1.- Se consideró como brote de C.U, sin tener evidencia endoscópica del mismo, previo a trat con Corticoides
2.- Hablan de brote, pero no se aportan si en la pieza se objetivaron datos de actividad inflamatoria en el resto del colon. 3.- Se realizó estudio de CMV con IHQ+/- PCR?.
4.- La perforación podría estar en relación con el tratamiento esteroideo


References
1- Ciccocioppo R, Racca F, Scudeller L et al. Differential cellular localization of Epstein-Barr virus and human cytomegalovirus in the colonic mucosa of patients with active or quiescent inflammatory bowel disease. Immunol Res 2016; 64: 191–203.
2- Maffione AM, Rampin L, Paolini R, et al. Epstein-Barr virus-positive mucocutaneous ulcer mimicking rectal carcinoma at 18F-FDG PET/CT. Clin Nucl Med. 2017;42(8):2016-2017.
3- Li X, Chen N, You P et al. The Status of Epstein-Barr Virus Infection in Intestinal Mucosa of Chinese Patients with Inflammatory Bowel Disease. Digestion. 2019;99(2):126-132.
4- Rein Willemze, Lorenzo Cerroni, Werner Kempf et al. The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas. Blood 2019 :blood-2018-11-881268.
5- Bunn B, Van Heerden W. EBV-positive mucocutaneous ulcer of the oral cavity associated with HIV/AIDS. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015;120(6):725-732.
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García-Romera Á, González-Díaz S, Ramos L. An acute episode of inflammatory bowel disease vs a rare manifestation of an Epstein-Barr virus-positive mucocutaneous ulcer. Case report. 6737/2019


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Publication history

Received: 08/11/2019

Accepted: 20/11/2019

Online First: 24/06/2020

Published: 08/07/2020

Article Online First time: 229 days

Article editing time: 243 days


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