Año 2024 / Volumen 116 / Número 2
Original
Ulcerative colitis overall disease severity index predicts colectomy: a prospective cohort study

77-82

DOI: 10.17235/reed.2023.9754/2023

Shengduo He, Hong Jiang, Yu Tian, Wei Zhang, Guigen Teng, Huahong Wang,

Resumen
Background: ulcerative colitis (UC) overall disease severity index (DSI) has been established. A prospective cohort study was performed to find the value of DSI to predict colectomy within one and four years and explored the association between DSI and other indexes. Methods: the hospitalized UC patients were enrolled from March 2018 to January 2019 in this single center study. DSI, Truelove and Witts criteria, Mayo index and Seo index were assessed by medical records. Outcome was whether to undergo colectomy within one and four years and was obtained by telephone survey or medical records. Index values of predicting colectomy within one and four years were evaluated using receiver operating characteristics (ROC) curves. Results: one hundred and thirty-eight of 233 hospitalized UC patients were enrolled. Within one year, the follow-up period was less than one year for six patients and two patients had died. A further nine patients underwent colectomy. The Spearman correlation coefficient between DSI and Truelove and Witts criteria, Mayo index and Seo index were 0.730, 0.839 and 0.843, respectively. Using these indices to predict colectomy within one and four years, the area under the curve of DSI was more than those of other indices and the cut-off value of DSI was 79. Conclusions: a good correlation of DSI with other indexes was demonstrated. DSI can be used to predict the need for colectomy within one or four years.
Resumen coloquial
Ulcerative colitis (UC) overall disease severity index (DSI) has been established. This study identified the value of DSI to predict colectomy within one and four years and explored the association between DSI and other indexes. The hospitalized UC patients were enrolled from March 2018 to January 2019 in this single center study. DSI and other indexes were assessed by medical records. Outcome was whether to undergo colectomy within one and four years and was obtained by telephone survey or medical records. The index value of predicting colectomy within one and four years was evaluated using receiver operating characteristics (ROC) curves. We enrolled 138 of 233 hospitalized UC patients. Nine patients underwent colectomy within one year. The Spearman correlation coefficient between DSI and Truelove&Witts criteria, Mayo index and Seo index was 0.730, 0.839, and 0.843, respectively. Using these indexes to predict colectomy within one and four years, the area under the curve of DSI was more than those of other indexes. We demonstrated DSI had a good correlation with other indexes. DSI can be used to predict the need for colectomy within one or four years.
Share Button
Nuevo comentario
Comentarios
No hay comentarios para este artículo.
Bibliografía
1. Cosnes, J., C. Gowerrousseau, P. Seksik et al., Epidemiology and natural history of inflammatory bowel diseases. Gastroenterology,vol. 140,no. 6, pp. 1785-1794,2011.
2. Molodecky, N.A., I.S. Soon, D.M. Rabi et al., Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology,vol. 142,no. 1, pp. 46-54,2012.
3. Jiang, X.L. H.F. Cui, An analysis of 10218 ulcerative colitis cases in China. World Journal of Gastroenterology,vol. 8,no. 1, pp. 158-161,2002.
4. Zeng, Z., Z. Zhu, Y. Yang et al., Incidence and clinical characteristics of inflammatory bowel disease in a developed region of Guangdong Province, China: a prospective population-based study. Journal of Gastroenterology and Hepatology,vol. 28,no. 7, pp. 1148-1153,2013.
5. Walsh, A.J., R.V. Bryant S.P.L. Travis, Current best practice for disease activity assessment in IBD. Nature Reviews Gastroenterology & Hepatology,vol. 13,no. 567,2016.
6. Schroeder, K.W., W.J. Tremaine D.M. Ilstrup, Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. New England Journal of Medicine,vol. 317,no. 26, pp. 1625-1629,1987.
7. Truelove, S.C. L.J. Witts, Cortisone in ulcerative colitis; final report on a therapeutic trial. British Medical Journal,vol. 2,no. 4947, pp. 1041-1048,1955.
8. Harbord, M., R. Eliakim, D. Bettenworth et al., Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 2: Current Management. Journal of Crohn's & Colitis,vol. 11,no. 7, pp. 769-784,2017.
9. Ferrante, M., S. Declerck, G. De Hertogh et al., Outcome after proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis. Inflammatory Bowel Diseases,vol. 14,no. 1, pp. 20-28,2008.
10. Leijonmarck, C.E., P.G. Persson G. Hellers, Factors affecting colectomy rate in ulcerative colitis: an epidemiologic study. Gut,vol. 31,no. 3, pp. 329-333,1990.
11. Ho, G.T., C. Mowat, C.J. Goddard et al., Predicting the outcome of severe ulcerative colitis: development of a novel risk score to aid early selection of patients for second-line medical therapy or surgery. Alimentary Pharmacology and Therapeutics,vol. 19,no. 10, pp. 1079-1087,2004.
12. Hoie, O., F.L. Wolters, L. Riis et al., Low colectomy rates in ulcerative colitis in an unselected European cohort followed for 10 years. Gastroenterology,vol. 132,no. 2, pp. 507-515,2007.
13. Solberg, I.C., I. Lygren, J. Jahnsen et al., Clinical course during the first 10 years of ulcerative colitis: results from a population-based inception cohort (IBSEN Study). Scandinavian Journal of Gastroenterology,vol. 44,no. 4, pp. 431-440,2009.
14. Ananthakrishnan, A.N., E.L. McGinley, D.G. Binion et al., Simple score to identify colectomy risk in ulcerative colitis hospitalizations. Inflammatory Bowel Diseases,vol. 16,no. 9, pp. 1532-1540,2010.
15. Dias, C.C., P.P. Rodrigues, A. da Costa-Pereira et al., Clinical predictors of colectomy in patients with ulcerative colitis: systematic review and meta-analysis of cohort studies. Journal of Crohn's & Colitis,vol. 9,no. 2, pp. 156-163,2015.
16. Ananthakrishnan, A.N., M. Issa, D.B. Beaulieu et al., History of medical hospitalization predicts future need for colectomy in patients with ulcerative colitis. Inflammatory Bowel Diseases,vol. 15,no. 2, pp. 176-181,2009.
17. Seo, M., M. Okada, T. Yao et al., Evaluation of the clinical course of acute attacks in patients with ulcerative colitis through the use of an activity index. Journal of Gastroenterology,vol. 37,no. 1, pp. 29-34,2002.
18. Peyrin-Biroulet, L., J. Panés, W.J. Sandborn et al., Defining Disease Severity in Inflammatory Bowel Diseases: Current and Future Directions. Clinical Gastroenterology and Hepatology,vol. 14,no. 3, pp. 348-354,2016.
19. Koliani-Pace, J.L. C.A. Siegel, Beyond disease activity to overall disease severity in inflammatory bowel disease. The Lancet Gastroenterology and Hepatology,vol. 2,no. 9, pp. 624-626,2017.
20. Siegel, C.A., C.B. Whitman, B.M.R. Spiegel et al., Development of an index to define overall disease severity in IBD. Gut,vol. 67,no. 2, pp. 244-254,2018.
21. Magro, F., P. Gionchetti, R. Eliakim et al., Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extra-intestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders. Journal of Crohn's & Colitis,vol. 11,no. 6, pp. 649-670,2017.
22. Seo, M., M. Okada, T. Yao et al., An index of disease activity in patients with ulcerative colitis. American Journal of Gastroenterology,vol. 87,no. 8, pp. 971-976,1992.
23. Frolkis, A.D., J. Dykeman, M.E. Negrón et al., Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies. Gastroenterology,vol. 145,no. 5, pp. 996-1006,2013.
24. Macaluso, F.S., F. Cavallaro, C. Felice et al., Risk factors and timing for colectomy in chronically active refractory ulcerative colitis: A systematic review. Digestive and Liver Disease,vol.,2019.
25. D’Haens, G., W.J. Sandborn, B.G. Feagan et al., A Review of Activity Indices and Efficacy End Points for Clinical Trials of Medical Therapy in Adults With Ulcerative Colitis. Gastroenterology,vol. 132,no. 2, pp. 763-786,2007.
26. Burisch, J., K.H. Katsanos, D.K. Christodoulou et al., Natural Disease Course of Ulcerative Colitis during the First Five Years of Follow-up in a European Population-based Inception Cohort - An Epi-IBD Study. Journal of Crohn's and Colitis,vol. 13,no. 2, pp. 198-208,2019.
1. Cosnes, J., C. Gowerrousseau, P. Seksik et al., Epidemiology and natural history of inflammatory bowel diseases. Gastroenterology,vol. 140,no. 6, pp. 1785-1794,2011.
Artículos relacionados

Carta

Tofacitinib-induced eosinophilia

DOI: 10.17235/reed.2023.9831/2023

Carta

Perianal Paget’s disease

DOI: 10.17235/reed.2022.9304/2022

Carta

Chinese dragon sign of ulcerative colitis

DOI: 10.17235/reed.2022.9154/2022

Carta

Ulcerative colitis exacerbated by strongyloidiasis

DOI: 10.17235/reed.2022.9044/2022

Carta

Neumonitis intersticial por mesalazina en la era COVID

DOI: 10.17235/reed.2022.8635/2021

Carta

Efecto del Adacolumn® en colitis ulcerosa con COVID-19

DOI: 10.17235/reed.2020.7156/2020

Carta

Síndrome de Sweet en el brote grave de colitis ulcerosa

DOI: 10.17235/reed.2020.6995/2020

Carta al Editor

Colitis ulcerosa con afectación gástrica y duodenal

DOI: 10.17235/reed.2017.4685/2016

Original

Mercaptopurine and inflammatory bowel disease: the other thiopurine

DOI: 10.17235/reed.2016.4546/2016

Caso Clínico

Mesalamine-induced myopericarditis - A case report

DOI: 10.17235/reed.2016.4016/2015

Instrucciones para citar
He S, Jiang H, Tian Y, Zhang W, Teng G, Wang H, et all. Ulcerative colitis overall disease severity index predicts colectomy: a prospective cohort study . 9754/2023


Descargar en un gestor de citas

Descargue la cita de este artículo haciendo clic en uno de los siguientes gestores de citas:

Métrica
Este artículo ha sido visitado 712 veces.
Este artículo ha sido descargado 83 veces.

Estadísticas de Dimensions


Estadísticas de Plum Analytics

Ficha Técnica

Recibido: 30/05/2023

Aceptado: 20/08/2023

Prepublicado: 14/09/2023

Publicado: 07/02/2024

Tiempo de revisión del artículo: 70 días

Tiempo de prepublicación: 107 días

Tiempo de edición del artículo: 253 días


Compartir
Este artículo aun no tiene valoraciones.
Valoración del lector:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
La REED es el órgano oficial de la Sociedad Española de Patología Digestiva, la SociedadEspañola de Endoscopia Digestiva y la Asociación Española de Ecografía Digestiva
Política de cookies Política de Privacidad Aviso Legal © Copyright 2023 y Creative Commons. Revista Española de Enfermedades Digestivas