Año 2019 / Volumen 111 / Número 1
Revisión
Estratificación del riesgo y tratamiento de la colangitis biliar primaria

63-70

DOI: 10.17235/reed.2018.5662/2018

Javier Martínez, Lara Aguilera, Agustín Albillos,

Resumen
La colangitis biliar primaria es una enfermedad hepática crónica caracterizada por colestasis progresiva que puede evolucionar hacia cirrosis hepática. El tratamiento de elección es el ácido ursodesoxicólico, aunque en torno al 30% de los pacientes no responde. Estos pacientes presentan un peor pronóstico, por lo que deben ser detectados precozmente para ofrecerles alternativas terapéuticas. En esta línea, el mejor conocimiento de la fisiopatología de la enfermedad ha permitido el desarrollo de nuevos fármacos, como el ácido obeticólico y los fibratos. Esta revisión ofrece una perspectiva sobre la estratificación del riesgo de los pacientes y del tratamiento de esta enfermedad, desde el ácido ursodesoxicólico a las terapias de segunda línea.
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30/05/2020 1:20:46
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Martínez J, Aguilera L, Albillos A. Estratificación del riesgo y tratamiento de la colangitis biliar primaria. 5662/2018


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Ficha Técnica

Recibido: 18/04/2018

Aceptado: 11/09/2018

Prepublicado: 19/10/2018

Publicado: 17/01/2019

Tiempo de revisión del artículo: 139 días

Tiempo de prepublicación: 184 días

Tiempo de edición del artículo: 274 días


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