Year 2021 / Volume 113 / Number 4
Original
Outcomes of drug-induced acute pancreatitis: a ten-year experience of an academic center

276-279

DOI: 10.17235/reed.2020.7443/2020

Rubén Sánchez-Aldehuelo, Ana García García de Paredes, Diego Rojo Lázaro, Antonio Martínez Ortega, Irene García de la Filia Molina, Sergio López-Durán, Miguel Ángel Rodríguez-Gandía, Antonio López-Sanromán, Agustín Albillos,

Abstract
Background: drug-induced pancreatitis is an unexplored entity. Methods: a retrospective cohort study was performed at a referral center. Patients with drug-induced acute pancreatitis between 2008 and 2018 were included. Baseline patient characteristics, involved drugs, clinical course and recurrence were analyzed. Results: drug-induced pancreatitis represented 2.8 % of acute pancreatitis (47/1,665) and 18 different drugs were involved (thiopurines 61.8 %). The latency period was less than one month in 87.2 % of cases. Pancreatitis was mild in 89.3 % and recurrence risk was 2.3 %. Conclusion: drugs are a rare cause of pancreatitis, which mostly occurs within the first month of treatment, is usually mild and is associated with a low risk of recurrence.
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References
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Sánchez-Aldehuelo R, García García de Paredes A, Rojo Lázaro D, Martínez Ortega A, García de la Filia Molina I, López-Durán S, et all. Outcomes of drug-induced acute pancreatitis: a ten-year experience of an academic center. 7443/2020


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Publication history

Received: 27/07/2020

Accepted: 07/09/2020

Online First: 01/12/2020

Published: 07/04/2021

Article revision time: 40 days

Article Online First time: 127 days

Article editing time: 254 days


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