Year 2017 / Volume 109 / Number 8
Original
Clinical manifestations and endoscopic presentations of gastric lymphoma: a multicenter seven year retrospective survey

566-571

DOI: 10.17235/reed.2017.4882/2017

Xianghua Cui, Tao Zhou, Dalei Jiang, Huiya Liu, Jian Wang, Shengan Yuan, Hongyun Li, Peng Yan, Yanjing Gao,

Abstract
Background and aim: To improve the diagnostic rate of gastric lymphoma by analyzing clinical and endoscopic features of patients with gastric lymphoma and suspected gastric lymphoma. Methods: Clinical and endoscopic records of 35 patients with gastric lymphoma (positive group) and 133 patients with suspected gastric lymphoma but subsequent non-malignant pathology (negative group) were analyzed retrospectively. Data from another 99 gastric lymphoma patients with malignant pathology but nonspecific endoscopy (endoscopy non-suspect group) were analyzed. Results: Abdominal pain was the predominant symptom reported in both the positive and negative lymphoma groups, representing 60.0 and 52.5%, respectively. No significant differences in age, sex and clinical manifestations in subjects from the two groups were found. In the positive group, 54.3% were ulcerative; 34.3%, infiltrative; 8.5%, polypoid; and 2.9%, granulonodular. In the negative group, 52.6% were infiltrative; 42.1%, ulcerative; 4.5%, granulonodular; and 0.75%, polypoid. The endoscopic results varied between the two groups (p < 0.05). In the non-suspect group, 66.7% were ulcerative; 17.2%, infiltrative; 14.1%, polypoid; and 2.0%, granulonodular. With regards to histology, diffuse large B cell lymphoma was the most common subtype. The sensitivity of endoscopy was 60% for detecting malignancy and 21% for gastric lymphoma. Conclusion: The present study suggests that gastric lymphoma and suspected gastric lymphoma have similar clinical features. Gastric lymphoma presented mainly as macroscopic ulcerative lesions, whereas suspected gastric lymphoma appeared mainly as infiltrative lesions. Although the diagnostic rate of gastric lymphoma was relatively low (21%), it can be identified by endoscopy (60%). To improve diagnosis, repetitive endoscopic biopsies should be performed and novel endoscopic techniques developed in the future.
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Cui X, Zhou T, Jiang D, Liu H, Wang J, Yuan S, et all. Clinical manifestations and endoscopic presentations of gastric lymphoma: a multicenter seven year retrospective survey. 4882/2017


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Publication history

Received: 04/02/2017

Accepted: 12/04/2017

Online First: 15/06/2017

Published: 31/07/2017

Article revision time: 58 days

Article Online First time: 131 days

Article editing time: 177 days


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