Year 2022 / Volume 114 / Number 10
Letter
A rare complication of jejunal extension of a percutaneous endoscopic gastrostomy tube for levodopa-carbidopa intestinal gel administration

628-629

DOI: 10.17235/reed.2022.8806/2022

Pablo Olcina Domínguez, Félix González Martínez, Sergio Gil Rojas, María Belén López Moreno, Pablo Martínez Blanco, Jesús García-Cano Lizcano,

Abstract
Direct intestinal administration of levodopa-carbidopa gel has shown good results in selected patients with Parkinson's disease (1, 2). We want to present a complication related to the device necessary for the administration of this drug. A 58-year-old man, diagnosed with Parkinson's disease, treated for six months with levodopa-carbidopa intestinal gel, administered through a percutaneous endoscopic gastrostomy (PEG) tube with jejunal extension, presented at the emergency department for abdominal pain. The patient complained abdominal discomfort that lasted two months. It was described as pain around the umbilical area that radiated to the left lumbar region, worsened after ingestion, and did not subside with conventional analgesia.
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References
1. Wirdefeldt K, Odin P, Nyholm D. Levodopa-Carbidopa Intestinal Gel in Patients with Parkinson's Disease: A Systematic Review. CNS Drugs 2016; 30:381.
2. Lang AE, Rodriguez RL, Boyd JT, et al. Integrated safety of levodopa-carbidopa intestinal gel from prospective clinical trials. Mov Disord 2016; 31:538.
3. Moralejo Lozano Ó, Barrajón Masa AJ, Colmenares Bulgheroni M. Intestinal burying of the jejunal-tube of a PEG-J levodopa-carbidopa release system for Parkinson's disease. Successful endoscopic management. Rev Esp Enferm Dig. 2021;113(3):226-227. doi:10.17235/reed.2020.7180/2020
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Olcina Domínguez P, González Martínez F, Gil Rojas S, López Moreno M, Martínez Blanco P, García-Cano Lizcano J, et all. A rare complication of jejunal extension of a percutaneous endoscopic gastrostomy tube for levodopa-carbidopa intestinal gel administration. 8806/2022


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Publication history

Received: 21/03/2022

Accepted: 06/04/2022

Online First: 26/04/2022

Published: 07/10/2022

Article revision time: 13 days

Article Online First time: 36 days

Article editing time: 200 days


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