Year 2026 / Volume 118 / Number 3
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Cytomegalovirus infection as a rare cause of colitis

167-169

DOI: 10.17235/reed.2024.10435/2024

José María Rodríguez Lucas, Emilio Peña Ros, Francisco Miguel González Valverde,

Abstract
A 62 year-old-man with low anterior rectal resection and protective ileostomy, for low rectal neo and neoadjuvant QT +RT. Then ileostomy closure without incidences. On the 3rd postoperative day, he started with fever peaks and diarrhea. An abdominal CT scan showed diffuse thickening of the wall of the descending colon compatible with colitis and colonoscopy showed deep rectal ulcers with punch-like morphology with hyperemic mucosa with erythematous stippling of erosive appearance, showing this ulcerative pattern with numerous lesions and intensely edematous and congestive mucosa covered with abundant fibrinopurulent exudate in the descending colon. Biopsies and stool cultures were negative, but serologies were positive for CMV. Suspected CMV infection in a immunosuppressed by chemotherapy patient, he was treated with ganciclovir. The patient presented clinical improvement, without fever or diarrhea and improvement of the punch ulcers in the endoscopic controls, so he could be discharged from the hospital with follow-up in the outpatient consulting offices.
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References
1. Karigane D, Takaya S, Seki Y, Mastumoto Y, Onose A, Kosakai A, Sugaya N, Mori T. Cytomegalovirus enteritis in immunocompetent subjects: a case report and review of the literature. J Infect Chemother. 2014 May;20(5):325-9. doi: 10.1016/j.jiac.2013.12.004. Epub 2014 Jan 24. PMID: 24751234.
2. Lee CY, Chen YH, Lu PL. Reactivated cytomegalovirus proctitis in an immunocompetent patient presenting as nosocomial diarrhea: a case report and literature review. BMC Infect Dis. 2017 Feb 1;17(1):113. doi: 10.1186/s12879-017-2218-y. PMID: 28143418; PMCID: PMC5286859.
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Rodríguez Lucas J, Peña Ros E, González Valverde F. Cytomegalovirus infection as a rare cause of colitis. 10435/2024


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Publication history

Received: 26/03/2024

Accepted: 04/04/2024

Online First: 18/04/2024

Published: 06/03/2026

Article Online First time: 23 days

Article editing time: 710 days


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