Year 2018 / Volume 110 / Number 3
Letter to the Editor
Regenerative nodular hyperplasia, portal vein thrombosis and primary myelofibrosis: an unusual triple association.

209-210

DOI: 10.17235/reed.2018.5349/2017

Víctor Manuel Sández Montagut, Álvaro Giráldez Gallego, Guilermo Ontanilla Clavijo,

Abstract
We report a case of a regenerative nodular hyperplasia with a portal vein cavernomatosis with a subsequent progression to symptomatic, occlusive thrombosis of the superior mesenteric vein. A thorough investigation resulted in a final diagnosis of primary myelofibrosis associated with the V617F mutation in the JAK2 gene.
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References
1. Alvarez-Larrán A, Abraldes JG, Cervantes F, et al. Portal hypertension secondary to myelofibrosis: a study of three cases. Am J Gastroenterol 2005;100:2355-8.
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3. Bayan K, Tüzün Y, Yilmaz S, et al. Analysis of inherited thrombophilic mutations and natural anticoagulant deficiency in patients with idiopathic portal hypertension. J Thromb Thrombolysis 2009;28:57-62.
4. Tan HK, Leow WQ, Chang PE. Ruxolitinib for the treatment of portal hypertension in a patient with primary myelofibrosis. Gastroenterology. 2017 May 4. pii: S0016- 5085(16)35073-9. [Epub ahead of print]
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Sández Montagut V, Giráldez Gallego Á, Ontanilla Clavijo G. Regenerative nodular hyperplasia, portal vein thrombosis and primary myelofibrosis: an unusual triple association. . 5349/2017


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Publication history

Received: 31/10/2017

Accepted: 02/11/2017

Online First: 25/01/2018

Published: 28/02/2018

Article Online First time: 86 days

Article editing time: 120 days


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