Año 2024 / Volumen 116 / Número 10
Carta
Intestinal perforation caused by Epstein-Barr virus-positive primary diffuse large B-cell lymphoma in a patient with human immunodeficiency virus

581-582

DOI: 10.17235/reed.2023.10124/2023

Qiuli Liu, Qun Bao, Bin Zhao, Kaidong Chen, Xiaojian Weng,

Resumen
We report the case of a 48-year-old male who presented with right lower abdominal pain and a mass for 2 weeks and got constipation for 5 days. An abdominal CT scan conducted before admission at other hospitals revealed an obstruction in the blind ascending colon, which was suspected to be a malignant tumor. Proctoscopy revealed peritoneal implantation metastasis and multiple pelvic lymph nodes. Physical examination was unremarkable except for multiple lymph node enlargements in the inguinal area, without pain. A whole-body contrast-enhanced FDG-PET/CT revealed lymphoma involvement in the ascending colon, peritoneum, bone marrow, and lymph nodes in multiple regions of the body, with DLBCL as a suspected diagnosis. Pathological findings from the colonoscopy revealed atypical lymphocyte infiltration and Immunostaining indicated the presence of atypical lymphocytes with Ki-67 (90%) and tested positive for CD20, CD19, CD10, and BCL-6. Based on the above findings, stage IV DLBCL was diagnosed. Furthermore, EBV-DNA amplification was positive. The patient received R-CHOP treatment for 2 days before experiencing symptoms of fevers, chills, and abdominal pain. He underwent emergency surgery due to intestinal perforation, and preoperative blood tests revealed HIV-positive. The prognosis for the patient is poor due to sepsis.
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Instrucciones para citar
Liu Q, Bao Q, Zhao B, Chen K, Weng X. Intestinal perforation caused by Epstein-Barr virus-positive primary diffuse large B-cell lymphoma in a patient with human immunodeficiency virus. 10124/2023


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Ficha Técnica

Recibido: 28/11/2023

Aceptado: 04/12/2023

Prepublicado: 14/12/2023

Publicado: 09/10/2024

Tiempo de prepublicación: 16 días

Tiempo de edición del artículo: 316 días


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