Year 2023 / Volume 115 / Number 5
Digestive Diseases Image
Don't burn the blanket to kill a flea: a case of intra-abdominal desmoid fibromatosis

259-260

DOI: 10.17235/reed.2022.8873/2022

Alexandra Libert, Mesut Mutluoglu, Stefaan Gryspeerdt, Veerle Mertens Gryspeerdt,

Abstract
A 39-year-old woman presented to the Emergency Department with dysuria and persistent abdominal pain for several weeks. The pain increased with palpation. Physical examination was otherwise normal. Computerized tomography (CT) scan revealed a round structure of unknown origin against the caecum and terminal ilium suspect for a GIST tumor and a fluid-filled right uterine tube suggestive of pyosalpinx. The following day a laparoscopic surgery with removal of the pyosalpinx and complete right hemi-colon including the suspected lesion was performed and biopsies of the surrounding peritoneum, meso and ileum were taken. Immunohistochemical tests (CD117/DOG1) and molecular analysis (KIT/PDGFRA) ruled out GIST. SMA and desmin were also negative. β-catenin along with next generation sequencing which revealed a likely pathogenic mutation in exon 3 of the CTNNB1 gene, suggested a diagnosis of desmoid-type fibromatosis (DF). Biopsies of the lymph nodes were negative.
Share Button
New comment
Comments
No comments for this article
References
1. Wu CE, Tzen CY, Wang SY, Yeh CN. Clinical Diagnosis of Gastrointestinal Stromal Tumor (GIST): From the Molecular Genetic Point of View. Cancers (Basel). 2019 May 16;11(5):679. doi: 10.3390/cancers11050679. PMID: 31100836; PMCID: PMC6563074.
2. Mullen JT, DeLaney TF, Rosenberg AE, Le L, Iafrate AJ, Kobayashi W, et al. β-Catenin mutation status and outcomes in sporadic desmoid tumors. Oncologist. 2013;18(9):1043-9.
3. Yao X, Corbett T, Gupta AA, Kandel RA, Verma S, Werier J, et al. A systematic review of active treatment options in patients with desmoid tumours. Curr Oncol. 2014;21(4):e613-e29.
Related articles

Letter

A rare cause of obscure gastrointestinal bleeding

DOI: 10.17235/reed.2022.9156/2022

Letter

GIST is not all that it seems

DOI: 10.17235/reed.2022.8974/2022

Editorial

Chronic intestinal failure: an overview and future perspectives

DOI: 10.17235/reed.2022.8827/2022

Digestive Diseases Image

Gastric gastrointestinal stromal tumor abscess

DOI: 10.17235/reed.2022.8580/2022

Letter

Basic training in gastrointestinal endoscopy: recording images

DOI: 10.17235/reed.2020.7385/2020

Letter

Desmoid fibromatosis of the esophagogastric junction

DOI: 10.17235/reed.2018.5630/2018

Letter to the Editor

Utility of neoadjuvant therapy in rectal GIST

DOI: 10.17235/reed.2017.4751/2016

Citation tools
Libert A, Mutluoglu M, Gryspeerdt S, Gryspeerdt V. Don't burn the blanket to kill a flea: a case of intra-abdominal desmoid fibromatosis. 8873/2022


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 487 visits.
This article has been downloaded 64 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 19/04/2022

Accepted: 26/04/2022

Online First: 29/04/2022

Published: 05/05/2023

Article Online First time: 10 days

Article editing time: 381 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology