Year 2015 / Volume 107 / Number 11
Editorial
PPIs: Between overuse and underprescription when really necessary

649-651

DOI: 10.17235/reed.2015.4022/2015

Carlos Martín de Argila de Prados, Lara Aguilera Castro, Enrique Rodríguez de Santiago,

Abstract
Hydrochloric acid gastric secretion plays, among its primary physiological foundations, a role as protective barrier against infection with external agents from the diet and also contributes to the digestion of ingested food. However, this secretion is a critical factor shared by a number of highly prevalent diseases involving the upper gastrointestinal tract. Paradigms of such conditions include gastroduodenal peptic ulcer and gastroesophageal reflux disease.
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References
1.- Koelz HR. Gastric acid in vertebrates. Scand J Gastroenterol 1992; 27 (Supl. 193): 2-6.
2.- Crónica de una revolución: Manejo de las enfermedades relacionadas con la secreción ácida del estómago. Martín de Argila de Prados C, Ed. Línea de Comunicación, Madrid 2015. Depósito legal: M-4419-2015.
3.- Esplugues JV. A pharmacological approach to gastric acid inhibition. Drugs 2005; 65 (Suppl 1): 7-12.
4.- Garner A, Fadlallah H, Parsons ME. 1976 and all that!-20 years of antisecretory therapy. Gut 1996; 39: 784-6.
5.- Subgrupos ATC y principios activos de mayor consumo en el Sistema Nacional de Salud en 2010 . Información terapéutica de la Seguridad Social 2011; 35: 124-8.
6.- Simó Miñana J. Use of prescription drugs in Spain and Europe. Aten Primaria 2012; 44: 335-47.
7.- Nardino RJ, Vender RJ, Herbert PN. Overuse of acid-suppressive therapy in hospitalized patients. Am J Gastroenterol 2000; 95: 3118-22.
8.- Ponce Romero M, Berenguer Lapuerta J. Indicaciones actuales de los inhibidores de la bomba de protones. Rev Clin Esp 2003; 203: 136-8.
9.- Gisbert JP, Martin de Argila de Prados C. Tratamiento de las enfermedades gastroenterológicas. Asociación Española de Gastroenterología, Ponce García J, editores. Úlcera péptica e infección por Helicobacter pylori. Barcelona: Elsevier; 2011. p. 109-21.
10.- Grupo de trabajo Sector Zaragoza I Salud. Empleo de los inhibidores de la bomba de protones en la prevención de gastropatías secundarias a fármacos. Guía de Práctica Clínica. Enero 2012. Disponible en: http://www.guiasalud.es/GPC/GPC_509_IBP_gastropatias_2rias_fcos_completa.pdf.
10.- Ramirez E, Lei SH, Borobia AM, et al. Overuse of PPIs in patients at admission, during treatment, and at discharge in a tertiary Spanish hospital. Curr Clin Pharmacol 2010; 5: 288-97.
11.- Reimer C. Safety of long-term PPI therapy. Best Pract Res Clin Gastroenterol 2013; 27: 443-54.
12.- Villamañan E, Ruano M, Lara C, et al. Reasons for initiation of proton pump inhibitor therapy for hospitalised patients and its impact on outpatient prescription in primary car. Rev Esp Enf Digest ¿? Es la cita del artículo de la Editorial y no sé sus datos de publicación, a añadir por la REED.
13.- Naunton M, Peterson GM, Bleasel MD. Overuse of proton pump inhibitors. J Clin Pharm Ther 2000; 25: 333-40.
14.- van Vliet EP, Otten HJ, Rudolphus A et al. Inappropriate prescription of proton pump inhibitors on two pulmonary medicine wards. Eur J Gastroenterol Hepatol 2008; 20: 608-12.
15.- Eid SM, Boueiz A, Paranji S et al. Patterns and predictors of proton pump inhibitor overuse among academic and non-academic hospitalists. Intern Med 2010; 49: 2561-8.
16.- Zink DA, Pohlman M, Barnes M et al. Long-term use of acid suppression started inappropriately during hospitalization. Aliment Pharmacol Ther 2005; 21: 1203-9.
17.- Martín-Echevarría E, Pereira Juliá A, Torralba M et al. Assessing the use of proton pump inhibitors in an internal medicine department. Rev Esp Enferm Dig 2008; 100: 76-81.
18.- Zink DA, Pohlman M, Barnes M et al. Long-term use of acid suppression started inappropriately during hospitalization. Aliment Pharmacol Ther. 2005; 21: 1203-9.
19.- Pham CQ, Regal RE, Bostwick TR et al. Acid suppressive therapy use on an inpatient internal medicine service. Ann Pharmacother 2006; 40: 1261-6.
20.- Noguerado Asensio A, Rodríguez Barrientos R, Zelaya Castro P et al. Use of acid-suppressive medications in hospitalized patients. An Med Intern 2002; 19: 557-60.
21.- American Society of Health-System Pharmacists. ASHP Therapeutic Guidelines on stress ulcer prophylaxis. Am J Health Syst Pharm 1999; 56: 347–79.
22.- Heidelbaugh JJ, Goldberg KL, Inadomi JM. Overutilization of proton pump inhibitors: a review of cost-effectiveness and risk. Am J Gastroenterol 2009; 104 (Suppl 2): S27-32.
23.- Dellinger RP, Carlet JM, Masur H et al. Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Crit Care Med 2004; 32: 858-73.
24.- de Burgos Lunar C, Novo del Castillo S, Llorente Díaz E et al. Study of prescription-indication of proton pump inhibitors. Rev Clin Esp 2006; 206: 266-70.
25.- Lanas A, Ferrández A. Inappropriate prevention of NSAID-induced gastrointestinal events among long-term users in the elderly. Drugs Aging 2007; 24: 121-31.
26.- Batuwitage BT, Kingham JG, Morgan NE et al. Inappropriate prescribing of proton pump inhibitors in primary care. Postgrad Med J 2007; 83: 66-8.
27.- Lanas A, Esplugues JV, Zapardiel J et al. Education-based approach to addressing non-evidence-based practice in preventing NSAID-associated gastrointestinal complications. World J Gastroenterol 2009; 15: 5953-9.
28.- Grant K, Al-Adhami N, Tordoff J et al. Continuation of proton pump inhibitors from hospital to community. Pharm World Sci 2006; 28: 189-93.
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Martín de Argila de Prados C, Aguilera Castro L, Rodríguez de Santiago E. PPIs: Between overuse and underprescription when really necessary. 4022/2015


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Publication history

Received: 29/09/2015

Accepted: 30/09/2015

Online First: 26/10/2015

Published: 30/10/2015

Article Online First time: 27 days

Article editing time: 31 days


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