Año 2026 / Volumen 118 / Número 1
Carta
Ruptured pancreatic carcinosarcoma – A case of extended survival following surgical resection and chemotherapy

60-62

DOI: 10.17235/reed.2024.10856/2024

Yekai Zhou, Xiaorong Chen, Jie Li, Fang Luo,

Resumen
We present a rare case of ruptured pancreatic carcinosarcoma in a 56-year-old male who underwent radical surgery and adjuvant chemotherapy. Despite the typical poor prognosis associated with this aggressive tumor, the patient achieved an overall survival of 20 months postoperatively. This case emphasizes the challenges in diagnosing and managing pancreatic carcinosarcoma and highlights the potential benefits of aggressive surgical and chemotherapeutic interventions in achieving extended survival
Nuevo comentario
Comentarios
No hay comentarios para este artículo.
Bibliografía
1.Zhu, W. Y.; Liu, T. G.; Zhu, H., Long-term recurrence-free survival in a patient with pancreatic carcinosarcoma: a case report with a literature review. Med Oncol 2012, 29 (1), 140-3.
2.Yamazaki, K., A unique pancreatic ductal adenocarcinoma with carcinosarcomatous histology, immunohistochemical distribution of hCG-beta, and the elevation of serum alpha-feto-protein. J Submicrosc Cytol Pathol 2003, 35 (4), 343-9.
3.Millis, J. M.; Chang, B.; Zinner, M. J.; Barsky, S. H., Malignant mixed tumor (carcinosarcoma) of the pancreas: a case report supporting organ-induced differentiation of malignancy. Surgery 1994, 115 (1), 132-7.
4.van den Berg, W.; Tascilar, M.; Offerhaus, G. J.; Albores-Saavedra, J.; Wenig, B. M.; Hruban, R. H.; Gabrielson, E., Pancreatic mucinous cystic neoplasms with sarcomatous stroma: molecular evidence for monoclonal origin with subsequent divergence of the epithelial and sarcomatous components. Mod Pathol 2000, 13 (1), 86-91.
5.Kim, H. S.; Joo, S. H.; Yang, D. M.; Lee, S. H.; Choi, S. H.; Lim, S. J., Carcinosarcoma of the pancreas: a unique case with emphasis on metaplastic transformation and the presence of undifferentiated pleomorphic high-grade sarcoma. J Gastrointestin Liver Dis 2011, 20 (2), 197-200.
6.Szukala, S. A.; Marks, J. R.; Burchette, J. L.; Elbendary, A. A.; Krigman, H. R., Co-expression of p53 by epithelial and stromal elements in carcinosarcoma of the female genital tract: an immunohistochemical study of 19 cases. Int J Gynecol Cancer 1999, 9 (2), 131-136.
7.Jia, Z.; Zhang, K.; Huang, R.; Zhou, X.; Jiang, L., Pancreatic carcinosarcoma with rare long-term survival: Case report and review of the literature. Medicine (Baltimore) 2017, 96 (4), e5966.
8.Liu, X.; Wang, H.; Ying, R., Comparative study of sarcomatoid carcinoma and carcinosarcoma of the pancreas: a population-based study. Transl Cancer Res 2022, 11 (7), 2061-2069.
9.Collisson, E. A.; Sadanandam, A.; Olson, P.; Gibb, W. J.; Truitt, M.; Gu, S. D.; Cooc, J.; Weinkle, J.; Kim, G. E.; Jakkula, L.; Feiler, H. S.; Ko, A. H.; Olshen, A. B.; Danenberg, K. L.; Tempero, M. A.; Spellman, P. T.; Hanahan, D.; Gray, J. W., Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy. Nat Med 2011, 17 (4), 500-U140.
10.Zhu LX, Wang GS, Fan ST. Spontaneous rupture of hepatocellular carcinoma. Br J Surg 1996; 83: 602-607
11.Tanaka T, Yamanaka N, Oriyama T, Furukawa K, OkamotoE. Factors regulating tumor pressure in hepatocellularcarcinoma and implications for tumor spread. Hepatology 1997; 26: 283-287
1.Zhu, W. Y.; Liu, T. G.; Zhu, H., Long-term recurrence-free survival in a patient with pancreatic carcinosarcoma: a case report with a literature review. Med Oncol 2012, 29 (1), 140-3.
2.Yamazaki, K., A unique pancreatic ductal adenocarcinoma with carcinosarcomatous histology, immunohistochemical distribution of hCG-beta, and the elevation of serum alpha-feto-protein. J Submicrosc Cytol Pathol 2003, 35 (4), 343-9.(1)
3.Millis, J. M.; Chang, B.; Zinner, M. J.; Barsky, S. H., Malignant mixed tumor (carcinosarcoma) of the pancreas: a case report supporting organ-induced differentiation of malignancy. Surgery 1994, 115 (1), 132-7.
4.van den Berg, W.; Tascilar, M.; Offerhaus, G. J.; Albores-Saavedra, J.; Wenig, B. M.; Hruban, R. H.; Gabrielson, E., Pancreatic mucinous cystic neoplasms with sarcomatous stroma: molecular evidence for monoclonal origin with subsequent divergence of the epithelial and sarcomatous components. Mod Pathol 2000, 13 (1), 86-91.
5.Kim, H. S.; Joo, S. H.; Yang, D. M.; Lee, S. H.; Choi, S. H.; Lim, S. J., Carcinosarcoma of the pancreas: a unique case with emphasis on metaplastic transformation and the presence of undifferentiated pleomorphic high-grade sarcoma. J Gastrointestin Liver Dis 2011, 20 (2), 197-200.
6.Szukala, S. A.; Marks, J. R.; Burchette, J. L.; Elbendary, A. A.; Krigman, H. R., Co-expression of p53 by epithelial and stromal elements in carcinosarcoma of the female genital tract: an immunohistochemical study of 19 cases. Int J Gynecol Cancer 1999, 9 (2), 131-136.
7.Jia, Z.; Zhang, K.; Huang, R.; Zhou, X.; Jiang, L., Pancreatic carcinosarcoma with rare long-term survival: Case report and review of the literature. Medicine (Baltimore) 2017, 96 (4), e5966.
8.Liu, X.; Wang, H.; Ying, R., Comparative study of sarcomatoid carcinoma and carcinosarcoma of the pancreas: a population-based study. Transl Cancer Res 2022, 11 (7), 2061-2069.
9.Collisson, E. A.; Sadanandam, A.; Olson, P.; Gibb, W. J.; Truitt, M.; Gu, S. D.; Cooc, J.; Weinkle, J.; Kim, G. E.; Jakkula, L.; Feiler, H. S.; Ko, A. H.; Olshen, A. B.; Danenberg, K. L.; Tempero, M. A.; Spellman, P. T.; Hanahan, D.; Gray, J. W., Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy. Nat Med 2011, 17 (4), 500-U140.
10.Zhu LX, Wang GS, Fan ST. Spontaneous rupture of hepatocellular carcinoma. Br J Surg 1996; 83: 602-607
11.Tanaka T, Yamanaka N, Oriyama T, Furukawa K, OkamotoE. Factors regulating tumor pressure in hepatocellularcarcinoma and implications for tumor spread. Hepatology 1997; 26: 283-287
12. Ozden S, Haliloglu B, Ilter E, Akin FT, Kebudi A, Peker O. An extremely rare cause of acute abdomen in pregnancy ruptured pancreatic mucinous Cystadenocarcinoma. Pancreas. 2007;34:474–6.
13. Bergenfeldt M, Poulsen IM, Hendel HW, Serizawa RR. Pancreatic ascites due to rupture of a mucinous cystic neoplasm. Acta Oncol. 2008;47:978–81.
14. Panieri E, Krige JE, Bornman PC, Graham SM, Terblanche J, Cruse JP. Operative Management of Papillary Cystic Neoplasms of the pancreas. J Am Coll Surg. 1998;186:319–24.
Artículos relacionados

Editorial

Cystic pancreatic lesions: when to watch and when to act?

DOI: 10.17235/reed.2025.11428/2025

Carta

Lymphocytic esophagitis and ringed esophagus

DOI: 10.17235/reed.2025.11273/2025

Carta

Ogilvie, cuando el tratamiento médico y endoscópico fracasan

DOI: 10.17235/reed.2024.10287/2024

Carta

Tratamiento endoscópico del esófago de Barrett

DOI: 10.17235/reed.2024.10201/2023

Imagen en Patología Digestiva

An unexpected finding between the Epstein-Barr virus and splenic rupture

DOI: 10.17235/reed.2023.9998/2023

Carta

Fístula cistogástrica espontánea: un hallazgo casual

DOI: 10.17235/reed.2023.9912/2023

Carta

Linfoma T hepatoesplénico y enfermedad inflamatoria intestinal

DOI: 10.17235/reed.2023.9472/2023

Carta

New technique for the endoscopic removal of long foreign bodies

DOI: 10.17235/reed.2023.9398/2022

Carta

An uncommon colonic polyp

DOI: 10.17235/reed.2022.9160/2022

Carta

POEMS syndrome: an uncommon cause of peritoneal effusion

DOI: 10.17235/reed.2021.8027/2021

Imagen en Patología Digestiva

Phlebosclerotic colitis: an unusual cause of abdominal pain and hematochezia

DOI: 10.17235/reed.2020.7358/2020

Carta

Sarcoma hepático roto como causa de abdomen agudo

DOI: 10.17235/reed.2019.6163/2019

Original

Apendicopatía neurogénica. A propósito de 8 casos

DOI: 10.17235/reed.2017.4520/2016

Carta al Editor

Rupture of esophagus by compressed air

DOI: 10.17235/reed.2016.4307/2016

Caso Clínico

Melanoma esofágico primario: descripción de un caso

DOI: 10.17235/reed.2016.3908/2015

Carta al Editor

Descripción de un caso de evolución inusual de apendicitis epiploica

DOI: 10.17235/reed.2015.3796/2015

Carta al Editor

Rotura esplénica tras colonoscopia de cribado de cáncer colorrectal

DOI: 10.17235/reed.2015.3714/2015

Instrucciones para citar
Zhou Y, Chen X, Li J, Luo F. Ruptured pancreatic carcinosarcoma – A case of extended survival following surgical resection and chemotherapy. 10856/2024


Descargar en un gestor de citas

Descargue la cita de este artículo haciendo clic en uno de los siguientes gestores de citas:

Métrica
Este artículo ha sido visitado 1219 veces.
Este artículo ha sido descargado 17 veces.

Estadísticas de Dimensions


Estadísticas de Plum Analytics

Ficha Técnica

Recibido: 11/10/2024

Aceptado: 27/10/2024

Prepublicado: 12/11/2024

Publicado: 14/01/2026

Tiempo de prepublicación: 32 días

Tiempo de edición del artículo: 460 días


Compartir
Este artículo aun no tiene valoraciones.
Valoración del lector:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
La REED es el órgano oficial de la Sociedad Española de Patología Digestiva, la SociedadEspañola de Endoscopia Digestiva y la Asociación Española de Ecografía Digestiva
Política de cookies Política de Privacidad Aviso Legal © Copyright 2026 y Creative Commons. Revista Española de Enfermedades Digestivas