Year 2024 / Volume 116 / Number 3
Letter
Gastric mucormycosis presenting as diffuse thickening of the gastric wall with enhancement

167-168

DOI: 10.17235/reed.2023.9705/2023

Wenpeng Huang, Liming Li, Jianbo Gao, Lei Kang,

Abstract
We report the case of a 63-year-old woman who presented with abdominal distension and pain two months ago, which worsened after eating. An abdominal CT examination revealed uneven thickening of the gastric wall on the greater curvature side of the gastric body, with progressive obviously enhancement. She was then examined by an upper endoscopy, which showed mucosal swelling on the greater curvature side of the lower gastric body with exudation of necrotic materials. Biopsies of the lesion were taken and histological results revealed a large number of broad-based and non-septate hyphae, with positive expression of PAS (Periodic Acid-Schiff) and hexamine silver stains, The patient was treated with amphotericin B liposomal antifungal therapy and remained under surveillance for six months without evidence of disease progression by follow-up upper endoscopy.
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References
[1] Ss G, P S, Tbs B, et al. CT appearance of gastrointestinal tract mucormycosis[J]. Abdominal Radiology (New York), 2021, 46(5). DOI: 10.1007/s00261-020-02854-3.
[2] Patel A, Kaur H, Xess I, et al. A multicentre observational study on the epidemiology, risk factors, management and outcomes of mucormycosis in India[J]. Clin Microbiol Infect, 2020, 26(7):944.e9-944.e15. DOI: 10.1016/j.cmi.2019.11.021.
[3] Skiada A, Lass-Floerl C, Klimko N, et al. Challenges in the diagnosis and treatment of mucormycosis[J]. Med Mycol, 2018, 56(suppl_1):93-101. DOI: 10.1093/mmy/myx101.
[4] Wang C, Yang Q, Liu N, et al. Emphysematous gastritis associated with mucormycosis in a patient with fulminant myocarditis requiring veno-arterial extracorporeal membrane oxygenation[J]. Rev Esp Enferm Dig, 2022, 114(4):236-237. DOI: 10.17235/reed.2021.8477/2021.
[5] Uchida T, Okamoto M, Fujikawa K, et al. Gastric mucormycosis complicated by a gastropleural fistula: A case report and review of the literature[J]. Medicine (Baltimore), 2019, 98(48):e18142. DOI: 10.1097/MD.0000000000018142.
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Huang W, Li L, Gao J, Kang L. Gastric mucormycosis presenting as diffuse thickening of the gastric wall with enhancement. 9705/2023


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Publication history

Received: 04/05/2023

Accepted: 05/05/2023

Online First: 19/05/2023

Published: 04/03/2024

Article Online First time: 15 days

Article editing time: 305 days


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