Year 2017 / Volume 109 / Number 8
Letter to the Editor
Use of abdominal ultrasound in the diagnosis of hepatic sinusoidal obstruction syndrome (SOS) in a patient receiving a hematopoietic-cell transplant

608-609

DOI: 10.17235/reed.2017.4823/2017

Marta Abadía Barnó, Eva Marín Serrano, Gloria Ruiz Fernández,

Abstract
The sinusoidal obstruction syndrome (SOS) is an uncommon form of portal hypertension that occurs in hematopoietic-cell transplant recipients who receive intense conditioning treatments. The diagnosis is clinical and it is usually delayed, because in these patients there are many causes that can damage the liver and can delay its detection. We present the case of a 47-year-old man, whose diagnosis was made with clinical and analytical data supported by ultrasound signs that showed hepatic congestion. After treatment with defibrotide the patient improved clinically and analytically. Hepatic vascularization and perfusion also improved. Therefore, abdominal doppler ultrasound is shown as a noninvasive exploration useful for the clinical management of SOS and as an early marker of good clinical evolution.
Share Button
New comment
Comments
No comments for this article
References
1. Dignan FL, Wynn RF, Hadzic N, et al. BCSH/BSBMT guideline: Diagnosis and management of veno-occlusive disease (sinusoidal obstruction syndrome) following haematopoietic stem cell transplantation. Br J Haematol. 2013;163(4):444–57.
2. McDonald G.B, Sharma P, Matthews D.E, et al. Venocclusive disease of the liver after bone marrow transplantation: diagnosis, incidence, and predisposing factors. Hepatology. 1984;4(1):116-22
3. Rubbia-Brandt L. Sinusoidal Obstruction Syndrome. Clin Liver Dis. 2010;14(4):651–68
4. Fontanilla T, Hernando CG, Claros JC, et al. Acoustic radiation force impulse elastography and contrast-enhanced sonography of sinusoidal obstructive syndrome (Veno-occlusive Disease): preliminary results. J Ultrasound Med. 2011;30(11):1593–8.
5. Zhang L, Wang Y, Huang H, et al. Defibrotide for the prevention of hepatic veno-occlusive disease after hematopoietic stem cell transplantation: A systematic review. Clin Transplant. 2012;26(4):511–9.
Citation tools
Abadía Barnó M, Marín Serrano E, Ruiz Fernández G. Use of abdominal ultrasound in the diagnosis of hepatic sinusoidal obstruction syndrome (SOS) in a patient receiving a hematopoietic-cell transplant. 4823/2017


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 810 visits.
This article has been downloaded 171 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 02/01/2017

Accepted: 06/02/2017

Online First: 18/07/2017

Published: 31/07/2017

Article Online First time: 197 days

Article editing time: 210 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology