Year 2016 / Volume 108 / Number 9
Case Report
Rare association of celiac disease with myasthenia gravis in a patient with other immune disorders: a case report

586-588

DOI: 10.17235/reed.2016.3929/2015

Marcela de Almeida Menezes, Vírginia Lúcia Ribeiro Cabral, Sônia S. Lorena, Anamarli Nucci, Priscila Andrade Santana, Cecília Queiroz Silva,

Abstract
Background: Celiac disease is described in association with several autoimmune diseases, but rarely with myasthenia gravis. Case report: We describe the case of a 31-year-old white woman with celiac disease who presented manifestations related to a hyperactive immune system, including macroamylasemia, false-positive anti-HCV, positive antinuclear antibody, and Raynaud’s phenomenon. The introduction of a gluten-free diet (GFD) resolved these features, but myasthenia gravis (MG) symptoms unexpectedly occurred on that occasion. Discussion: The role of a GFD in the course of autoimmune diseases has been studied and improvement has been reported in many diseases. However, there is no consensus in the literature regarding the course of neurological disorders associated with celiac disease. In the present case, a GFD did not prevent the appearance of symptoms related to myasthenia gravis. There are few reports on the association of celiac disease with myasthenia gravis and therefore little is known about the course and time of onset of myasthenia in celiac patients. The present case increases the knowledge about this unusual autoimmune neurological disease associated with celiac disease.
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de Almeida Menezes M, Ribeiro Cabral V, Lorena S, Nucci A, Andrade Santana P, Queiroz Silva C, et all. Rare association of celiac disease with myasthenia gravis in a patient with other immune disorders: a case report. 3929/2015


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Publication history

Received: 16/07/2015

Accepted: 16/07/2015

Online First: 20/01/2016

Published: 06/09/2016

Article revision time: 0 days

Article Online First time: 188 days

Article editing time: 418 days


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