Año 2013 / Volumen 105 / Número 3
Imagen en Patología Digestiva
Gastric plasmablastic lymphoma in HIV-negative patient

pp. 166-167

Inês Marques, Ana Lagos and Beatriz Costa-Neves

Resumen
An 82-year-old female patient presented with melena, epi- gastric pain, progressive abdomen fullness and weight loss (8 kg) in the past 2 months. During physical examination, cutaneous pallor was evident and a large abdominal mass in epigastrium was palpable. There was no peripheric lym- phadenopathy or hepatosplenomegaly.
Blood count showed microcytic anemia and ferropenia (Hb = 7.5 g/dl, VGM = 79 fL; ferritin = 21 g/l, iron saturation = 23 %). Differential leukocyte counts, hepatic transaminase and lactate dehydrogenate levels were within normal limits.
Upper gastrointestinal endoscopy revealed large gastric body ulceration with areas of mucosal hyperemia and pallor (Fig. 1). Computed tomography of the abdomen (Fig. 2) showed diffuse wall thickening involving the gastric fundus, body and antrum.
Histological examination of the biopsy specimens revealed a diffuse, monomorphous proliferation of the tumour cells with features of immunoblasts, CD138, MUM-1, and kappa light chains positive (Fig. 3). These plasmablast-like features of tumour cells and lack of CD45 and B-cell associated antigens, disclosed the diagnosis of plasmablastic lymphoma (PBL).
Serology was negative for the human immunodeficiency virus (HIV), the electrophoretic pattern of serum proteins was normal and the bone marrow biopsy was free of lymphoma at histological evaluation.
The patient started treatment with CHOP (cyclophos- phamide, doxorubicin, vincristine, and prednisone) chemotherapy, but died before the second cycle was given.
Share Button
Nuevo comentario
Comentarios
No hay comentarios para este artículo.
Artículos relacionados
Instrucciones para citar
Inês Marques, Ana Lagos and Beatriz Costa-Neves. Gastric plasmablastic lymphoma in HIV-negative patient. 166-167


Descargar en un gestor de citas

Descargue la cita de este artículo haciendo clic en uno de los siguientes gestores de citas:

Métrica
Este artículo ha sido visitado 280 veces.
Este artículo ha sido descargado 11 veces.
Compartir
Este artículo ha sido valorado por 1 lectores .
Valoración del lector:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
La REED es el órgano oficial de la Sociedad Española de Patología Digestiva, la SociedadEspañola de Endoscopia Digestiva y la Asociación Española de Ecografía Digestiva
Política de cookies Política de Privacidad Aviso Legal © Copyright 2023 y Creative Commons. Revista Española de Enfermedades Digestivas