Year 2017 / Volume 109 / Number 10
Letter to the Editor
Hypersensitivity to azathioprine in a patient with Crohn’s disease: a case report

735

DOI: 10.17235/reed.2017.5031/2017

Mafalda Sousa, Luísa Proença, João Carvalho,

Abstract
Azathioprine (AZA) is commonly used in inflammatory bowel disease and many other medical diseases. The most common adverse events of AZA include gastrointestinal effects, hepatotoxicity, myelotoxicity and pancreatitis.
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References
1. Sinico RA, Sabadini E, Borlandelli S, et al. Azathioprine hypersensitivity: report of two cases and review of the literature. J Nephrol 2003; 16(2): 272-276
2. Schmitt K, Pfeiffer U, Stiehrle HE, et al. Absence of azathioprine hypersensitivity after administration of its active metabolite 6-mercaptopurine. Acta Derm Venereol 2000; 80: 147-148.
3. Godeau B, Paul M, Autegarden JE, et al. Hypersensitivity to azathioprine mimicking gastroenteritis. Absence of recurrence with 6-mercaptopurine. Gastroenterol Clin Biol 1995; 19: 117–119.
4. Corbett M, Schlup M. Azathioprine hypersensitivity mimicking underlying inflammatory bowel disease. Internal Medicine Journal 2001; 31: 366–367
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Sousa M, Proença L, Carvalho J. Hypersensitivity to azathioprine in a patient with Crohn’s disease: a case report. 5031/2017


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Publication history

Received: 26/04/2017

Accepted: 13/05/2017

Online First: 18/09/2017

Published: 29/09/2017

Article revision time: 4 days

Article Online First time: 145 days

Article editing time: 156 days


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