Year 2017 / Volume 109 / Number 6
Case Report
Fecal microbiota transplantation in recurrent Clostridium difficile infection in a patient with concomitant inflammatory bowel disease

473-476

DOI: 10.17235/reed.2017.4819/2016

Marta Gravito-Soares, Elisa Gravito-Soares, Francisco Portela, Manuela Ferreira, Carlos Sofia,

Abstract
The use of fecal microbiota transplantation in recurrent Clostridium difficile infection and coexistent inflammatory bowel disease remains unclear. A 61-year-old man with ulcerative pancolitis was diagnosed with a third recurrence of Clostridium difficile infection, previously treated with metronidazole, vancomycin and fidaxomicin. Fecal microbiota transplantation of an unrelated healthy donor was performed by the lower route. After a twelve month follow-up, the patient remains asymptomatic without Clostridium difficile infection relapses or inflammatory bowel disease flare-ups. Fecal microbiota transplantation is relatively simple to perform, well-tolerated, safe and effective in recurrent Clostridium difficile infection with ulcerative pancolitis, as an alternative in case of antibiotic therapy failure.
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References
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Gravito-Soares M, Gravito-Soares E, Portela F, Ferreira M, Sofia C. Fecal microbiota transplantation in recurrent Clostridium difficile infection in a patient with concomitant inflammatory bowel disease. 4819/2016


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Publication history

Received: 31/12/2016

Accepted: 27/01/2017

Online First: 16/05/2017

Published: 01/06/2017

Article revision time: 24 days

Article Online First time: 136 days

Article editing time: 152 days


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