Year 2017 / Volume 109 / Number 3
Digestive Diseases Image
Accumulation of mesalazine pills in the medium ileum in a patient with Crohn´s disease

219-220

Carmen Martínez Huertas, Paloma Garcia-Villanova Ruiz, José Pozo Sánchez, Cristina Dávila Arias,

Abstract
Crohn´s disease is an inflammatory disease that can involve any portion of the gastrointestinal tract, although terminal ileum is the most commonly affected portion. It is characterized by a transmural and discontinuous distribution pattern, with alternating periods of active disease and remission. We present the case of a 23-year-old patient diagnosed with Crohn´s disease, in treatment with extended release Mesalazine and corticoids. The CT Enterography showed activity signs and a great dilatation of medium ileum with lots of Mesalazine pills accumulated inside. Pill accumulation occurred because of stenosis, which did not let the pills at this level progress to distal ileum, and be absorbed.
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References
1. L. Moja, S. Danese, G. Fiorino et al. Systematic review with network meta-analysis: comparative efficacy and safety of budesonide and mesalazine (mesalamine) for Crohn’s disease. Aliment Pharmacol Ther 2015; 41: 1055–1065.
2. Siva P Raman, Karen M Horton, Elliot K Fishman. Computed tomography of Crohn’s disease: The role of three dimensional technique. World J Radiol 2013 May 28; 5(5): 193-201
3. Bei Ye, Daniel R van Langenberg. Mesalazine preparations for the treatment of ulcerative colitis: Are all created equal? World J Gastrointest Pharmacol Ther. 2015; 6(4): 137-144.
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Citation tools
Martínez Huertas C, Garcia-Villanova Ruiz P, Pozo Sánchez J, Dávila Arias C. Accumulation of mesalazine pills in the medium ileum in a patient with Crohn´s disease. 4427/2016


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Publication history

Received: 30/04/2016

Accepted: 14/05/2016

Published: 28/02/2017

Article revision time: 2 days

Article editing time: 304 days


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