Year 2022 / Volume 114 / Number 8
Letter
From metastasis to the primary tumor: Giant liver metastasis from a pancreatic neuroendocrine tumor

498-499

DOI: 10.17235/reed.2022.8758/2022

Elena Resina Sierra, José Carlos García-Gil, Alejandra Rosell Alayza, Alberto Ezquerra Durán, Raquel Muñoz González, Leticia González Moreno, María Caldas, Cecilio Santander Vaquero,

Abstract
We present the case of a 37-years old male, who consulted for an extended history of intermittent nausea and vomiting. Laboratory tests showed moderate elevated bilirubin (1.30 mg/dL) and GGT (106 U/L). An abdominal CT scan performed showed a solid 18-centimetres (cm) mass located in the right liver lobe. A biopsy of the lesion was performed, revealing metastastic cells of a well-differentiated neuroendocrine tumour (NET, G3 (Ki-67: 25%). Further study was performed with MRI, and SPECT-CT, showing a 2-cm lesion in the pancreatic tail suggestive of being the primary NET. Chromogranin A levels were high (114.100 ng/ml). In our case, despite the large size of the liver metastasis a full resection of the tumours was achieved.
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References
1. Pavel M, Öberg K, Falconi M, et al. Gastroenteropancreatic neuroendocrine neoplasms: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2020;31(7):844-860.
2. Howe JR, Merchant NB, Conrad C, et al. The North American Neuroendocrine Tumor Society Consensus Paper on the Surgical Management of Pancreatic Neuroendocrine Tumors. Pancreas. 2020;49(1):1-33.
3. González-Flores E, Serrano R, Sevilla I, et al. SEOM clinical guidelines for the diagnosis and treatment of gastroenteropancreatic and bronchial neuroendocrine neoplasms (NENs) (2018). Clin Transl Oncol. 2019;21(1):55-63. doi:10.1007/s12094-018-1980-7
4. Varas Lorenzo MJ. Neuroendocrine tumors - fascination and infrequency. Rev Esp Enferm Dig. 2009;101(3):195-208.
5. Frilling A, Modlin IM, Kidd M, et al. Recommendations for management of patients with neuroendocrine liver metastases. Lancet Oncol. 2014;15(1): e8-e21.
Citation tools
Resina Sierra E, García-Gil J, Rosell Alayza A, Ezquerra Durán A, Muñoz González R, González Moreno L, et all. From metastasis to the primary tumor: Giant liver metastasis from a pancreatic neuroendocrine tumor. 8758/2022


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Publication history

Received: 28/02/2022

Accepted: 01/03/2022

Online First: 08/03/2022

Published: 27/07/2022

Article Online First time: 8 days

Article editing time: 149 days


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