Year 2016 / Volume 108 / Number 8
Original
Usefulness of percutaneous elastography by acoustic radiation force impulse for the non-invasive diagnosis of chronic pancreatitis

450-456

DOI: 10.17235/reed.2016.4103/2015

Camilo Julio Llamoza-Torres, Maria Fuentes-Pardo, Francisco Javier Álvarez-Higueras, Fernando Alberca-de-las-Parras, Fernando Carballo-Álvarez,

Abstract
Objective: To determine the accuracy of the acoustic radiation force impulse (ARFI) technique for the diagnosis of chronic pancreatitis. Materials and methods: We present an observational, single-center study that included patients with suspected chronic pancreatitis in the period between October 2012 and September 2015 who underwent endoscopic ultrasound (EUS) and were classified according to the standard and Rosemont criteria. The same group of patients was assessed by the ARFI technology using ACUSON S2000™ equipment with Virtual Touch™ Quantification software for the assessment of pancreatic stiffness by obtaining the shear wave velocity (SWV) in the head, body and tail of the pancreas. Data were analyzed using ANOVA and nonparametric correlation methods. Diagnostic accuracy was obtained by analyzing receiver operating characteristic (ROC) curve. Results: A total of thirty-three patients were studied (45.5% women); mean age was 58.3 ± 11.8 years. Seventeen with a diagnosis of chronic pancreatitis and sixteen classified as normal according to standard criteria. A significant difference was detected between the means of SWV in pancreatic body of patients without (SWV: 1.27 m/s) and with chronic pancreatitis (SWV 1.57 m/s), p = 0.037. The area under the ROC curve was 71.3% (95% CI 0.532-0.895) and the accuracy of ARFI for diagnosing chronic pancreatitis was 69.7% for a SWV of 1.4 m/s in the pancreatic body. The SWV means in head (r = 0.421, p < 0.05) and body (r = 0.455, p < 0.05) of the pancreas showed a significant correlation with the number of EUS criteria for chronic pancreatitis. Conclusion: Quantification of pancreatic stiffness with ARFI elastography technique has proven to be useful for the non-invasive diagnosis of chronic pancreatitis.
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References
1. Luaces-Regueira M, Iglesias-García J, Lindkvist B, et al. Smoking as a risk factor for complications in chronic pancreatitis. Pancreas 2014;43:275-280.
2. Domínguez-Muñoz E, Lucendo A, Carballo F, et al. Estudio español multicéntrico de estimación de la prevalencia e incidencia de la pancreatitis crónica y sus complicaciones. Rev Esp Enferm Dig. 2014;106(4):239-245.
3. Wieserma MJ, Hawes RH, Lehman GA, et al. Prospective evaluation of endoscopic ultrasonography and endoscopy retrograde cholangiopancreatography in patients with chronic abdominal pain of suspected pancreatic origin. Endoscopy 1993;25:555-564.
4. Catalano MF, Sahai A, Levy M, et al. EUS-based criteria for the diagnosis of chronic pancreatitis: the Rosemont classification. Gastrointest Endosc 2009;69:1251-1261.
5. Stevens T, Lopez R, Adler DG, et al. Multicenter comparison of the interobserver agreement of standard EUS scoring and Rosemont classification scoring for the diagnosis of chronic pancreatitis. Gastrointest Endosc 2010:71:519-526.
6. Balci C. MRI assessment of chronic pancreatitis. Diagn Interv Radiol 2011;17:249-254.
7. Albashir S, Bronner MP, Paris MA, et al. Endoscopic ultrasound, secretin endoscopic pancreatic function test, and histology: correlation in chronic pancreatitis. Am J Gastroenterol 2010;105:2498-503.
8. Varadarajulu S, Eltoum I, Tamhane A, et al. Histopathologic correlates of noncalcific chronic pancreatitis by EUS: a prospective tissue characterization study. Gastrointest Endosc 2007;66:501-509.
9. Chong AK, Hawes RH, Hoffman BJ, et al. Diagnostic performance of EUS for chronic pancreatitis: a comparison with histopathology. Gastrointest Endosc 2007;65:808-814.
10. Le Blanc LJ, Chen JH, Al Haddad M, et al. Endoscopy ultrasound and histologhy in chronic pancreatitis: How are the associated? Pancreas 2014;43(3):440-4.
11. Vega-Peralta J, Attam R, Arain MA, et al. Correlation of EUS with histopathology in 50 patients undergoing total pancreatectomy (TP) with islet autotransplantation (IAT) for minimal change chronic pancreatitis (MCCP). Gastrointest Endosc 2011;73 Suppl:AB324
12. Shiina T. JSUM ultrasound elastography practice guidelines: basics and terminology. J Med Ultrasonics 2013:40:309-323.
13. Itoh Y, Takehara Y, Kawase T, et al. Feasibility of magnetic resonance elastography for the pancreas at 3T. J Magn Reson Imaging 2015. Jul 7. doi: 10.1002/jmri.24995.
14. Hirooka Y, Kuwahara T, Irisawa A, et al. JSUM ultrasound elastography practice guideline: pancreas. J Med Ultrasonics 2015;42:151-174.
15. Hirooka Y, Itoh A, Hashimoto S, et al. Utility of EUS:elastography in the diagnosis of pancreatic diseases. Gastrointest Endosc 2005;61:AB282.
16. Uchida H, Hirooka Y, Itoh A, et al. Utility of elastography in the diagnosis of pancreatic diseases using transabdominal ultrasonography. Gastroenterology 2005;128:A536-A536.
17. Gennisson JL, Deffieux T, Fink M, et al. Ultrasound elastography: Principles and techiniques. Diagnostic and Interventional Imaging 2013;94:487-495.
18. Friedrich-Rust M, Schlueter N, Smaczny C, et al. Non-invasive measurement of liver and páncreas fibrosis in patients with cystic fibrosis. J Cyst Fibros 2013;12 (5):431-9.
19. Yashima Y, Sasahira N, Isayama H, et al. Acoustic radiation force impulse elastography for noninvasive assessment of chronic pancreatitis. J Gastroenterol 2012:47:427-432.
20. Göya C, Hamidi C, Hattapoğlu S, et al. Use of accoustic radiation force impulse elastography to diagnose acute pancreatitis at hospital admission. J Ultrasound Med 2014;33:1453-1460.
21. Mateen M, Muheet K, Mohan R, et al. Evaluation of ultrasound based acoustic radiation force impulse (ARFI) and eSie touch Sonoelastography for diagnosis of inflammatory pancreatic diseases. J Pancreas 2012;13 (1):34-44.
22. Kawada N, Tanaka S, Uehara H, et al. Potencial use of point shear wave elastography for the pancreas: A single center prospective study. Eur J Radiol 2014;83:620-624.
23. Iglesias-García J, Domínguez-Muñoz E, Castiñeira-Alvariño M, et al. Quantitative elastography associated with endoscopic ultrasound for the diagnosis of chronic pancreatitis. Endoscopy 2013;45:781-788.
24. Kelly KA, Hollingsworth MA, Brand RE, et al. Advances in biomedical imaging, bioengineering, and related technologies for the development of biomarkers of pancreatic diseases. Pancreas 2015;44 (8):1185-1194.
25. Giovannini M, Hookey LC, Bories E, et al. Endoscopic Ultrasound Elastography: the First Step towards Virtual Biopsy? Preliminary Results in 49 patients. Endoscopy 2006;38:344-8.
26. Janssen J, Schlörer E, Greiner L. EUS elastography of the pancreas: feasibility and pattern description of the normal pancreas, chronic pancreatitis, and focal pancreatic lesions. Gastrointest Endosc 2007;65:971-8.
27. Itokawa F, Itoi T, Sofuni A, et al. EUS elastography combined with the strain ratio of tissue elasticity for diagnosis of solid pancreatic masses. J Gastroenterol 2011;46:843-853.
28. Mei M, Ni J, Liu D, et al. EUS elastography for diagnosis of solid pancreatic masses: a meta-analysis. Gastrointest Endosc 2013; 77 (4):578-589.
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Llamoza-Torres C, Fuentes-Pardo M, Álvarez-Higueras F, Alberca-de-las-Parras F, Carballo-Álvarez F. Usefulness of percutaneous elastography by acoustic radiation force impulse for the non-invasive diagnosis of chronic pancreatitis. 4103/2015


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Publication history

Received: 12/11/2015

Accepted: 12/04/2016

Online First: 26/07/2016

Published: 29/07/2016

Article revision time: 147 days

Article Online First time: 257 days

Article editing time: 260 days


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