Year 2020 / Volume 112 / Number 3
Editorial
Should we administer rectal anti-inflammatory drugs in all ERCPs in order to prevent pancreatitis? At least, it does not harm!

167-169

DOI: 10.17235/reed.2020.6871/2020

Jesús García-Cano, Miriam Viñuelas Chicano,

Abstract
Acute pancreatitis is the most common complication of endoscopic retrograde cholangio-pancreatography (ERCP). The sensitivity of the pancreas, which may respond with such violence to the slightest pressure exerted at the entrance to its main duct in the papilla of Vater, is even philosophically surprising. In fact, each touch on the papilla increases the potential for pancreatitis development. The initial stimulus resulting in obstruction of pancreatic secretion may be the edema caused by the catheter's physical contact, the thermal effect of sphincterotomy, or the overdistension induced by the injected contrast. The triggering fact is followed by a release of inflammatory cytokines, which induce changes in pancreatic microcirculation.
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05/03/2020 20:28:32
Buen temario


References
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García-Cano J, Viñuelas Chicano M. Should we administer rectal anti-inflammatory drugs in all ERCPs in order to prevent pancreatitis? At least, it does not harm!. 6871/2020


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Publication history

Received: 10/01/2020

Accepted: 10/01/2020

Online First: 27/01/2020

Published: 05/03/2020

Article Online First time: 17 days

Article editing time: 55 days


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