Year 2019 / Volume 111 / Number 11
Case Report
Using octreotide for refractory ascites after liver transplantation

882-884

DOI: 10.17235/reed.2019.6316/2019

Oana-Anisa Nutu, Alejandro Manrique Municio, Alberto Marcacuzco Quinto, Jorge Calvo Pulido, Carlos Jiménez Romero,

Abstract
Refractory ascites is a condition associated with a reduced survival and a poorer quality of life. Portal hyperflow after liver transplantation is one of the main causes. We report the case of a female patient with refractory ascites after liver transplantation who was treated with splenic embolization. Ascites persisted despite embolization due to splenic revascularization by short gastric vessels and repeat embolization was technically unfeasible. Based on pathophysiology data, she was treated with octreotide, a somatostatin octapeptide analog, which resulted in splanchnic vasoconstriction and a reduction of the portal flow and venous pressure. After four months of treatment with octreotide, the patient had a good clinical status without ascites.
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References
1. Gotthardt D, Weiss K, Rathenberg V, et al. Persistent ascites after liver transplantation: etiology, treatment and impact on survival. Ann Transplan 2013; 18: 378-383
2. Pravisani R, Baccarani U, Adani G, et al. Splenic artery syndrome as a possible cause of late onset refractory ascites after liver transplantation: management with proximal splenic artery embolization. Transplantation Proc 2016; 48: 377-379
3. Wang C, Zhao X, Shengyi Y. Efficacy of the prophylactic use of octreotide for the prevention of complications after pancreatic resection. An update systematic review and meta-analysis of randomized controlled trials. Medicine (Baltimore) 2017; 96: e7500
4. Troisi R, Vanlander A, Giglio M, et al. Somatostatin as inflow modulator in liver transplant recipients with severe portal hypertension. Ann Surg 2018 doi 10.1097/SLA0000000000003062
5. Eipel C, Abshagen K, Vollmar B. Regulation of hepatic blood flow: The hepatic arterial buffer response revisited. World J Gastroenterol 2010; 16: 6046-6057
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Nutu O, Manrique Municio A, Marcacuzco Quinto A, Calvo Pulido J, Jiménez Romero C. Using octreotide for refractory ascites after liver transplantation. 6316/2019


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Publication history

Received: 02/04/2019

Accepted: 07/06/2019

Online First: 09/10/2019

Published: 07/11/2019

Article revision time: 21 days

Article Online First time: 190 days

Article editing time: 219 days


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