Year 2020 / Volume 112 / Number 6
Original
Comparison of the AIMS65 score with the Glasgow-Blatchford and Rockall scoring systems for the prediction of the risk of in-hospital death among patients with upper gastrointestinal bleeding

467-473

DOI: 10.17235/reed.2020.6496/2019

Xuefeng Lu, Xiaojie Zhang, Hong Chen,

Abstract
Objective: the aim of this study was to compare the AIMS65, Glasgow-Blatchford score (GBS) and Rockall score for the prediction of the risk of in-hospital death among patients with upper gastrointestinal bleeding (UGIB). Methods: patients with UGIB admitted to the ZhongDa hospital from June 2015 to July 2017 were retrospectively collected. All patients were assessed by the AIMS65, GBS and Rockall score and the main outcomes were in-hospital mortality. Odds ratios (OR) and 95 % confidence interval (CI) were estimated to assess the association of the three scores with the risk of death using logistic regression models. Subsequently, their risk stratification accuracy were compared. Finally, their predictive power was compared using the area under the receiver operating characteristic curve (AUROC). Results: of the 284 UGIB patients enrolled in the study, 51 (18.0 %) had variceal bleeding (VUGIB) and 10 patients (3.5 %) died. AIMS65 (OR = 5.14, 95 % CI = 2.48, 10.64), GBS (OR = 1.66, 95 % CI = 1.28, 2.15) and Rockall (OR = 2.72, 95 % CI = 1.76, 4.18) scores were positively associated with death risk among all patients. The AIMS65 score (high-risk group vs low-risk group: 11.9 % vs 0.0 %, p < 0.001) was effective to classify high-risk in-hospital deaths populations. The AIMS65 score was the best approach to predict in-hospital death among all UGIB patients (AUROC: AIMS65 0.955, GBS 0.882, Rockall 0.938), NVUGIB patients (AUROC = 0.969, 95 % CI = 0.937, 0.989) or VUGIB patients (AUROC = 0.885, 95 % CI = 0.765, 0.967). Conclusions: the AIMS65 score is the most convenient UGIB prognostic score to predict in-hospital mortality and may be more suitable for patients with NVUGIB.
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References
1. Lau J Y, Sung J, Hill C, et al. Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality(J). Digestion, 2011,84(2):102-113.
2. Barkun A N, Bardou M, Kuipers E J, et al. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding(J). Ann Intern Med, 2010,152(2):101-113.
3. Jairath V, Martel M, Logan R F, et al. Why do mortality rates for nonvariceal upper gastrointestinal bleeding differ around the world? A systematic review of cohort studies(J). Can J Gastroenterol, 2012,26(8):537-543.
4. Del P M, Bianco M A, Cipolletta L, et al. The "Prometeo" study: online collection of clinical data and outcome of Italian patients with acute nonvariceal upper gastrointestinal bleeding(J). J Clin Gastroenterol, 2013,47(4):e33-e37.
5. Laine L, Jensen DM. Management of patients with ulcer bleeding(J). Am J Gastroenterol. 2012;107:345–60.
6. Pang SH, Ching JY, Lau JY, et al. Comparing the Blatchford and pre-endoscopic Rockall score in predicting the need for endoscopic therapy in patients with upper GI hemorrhage. Gastrointest Endosc 2010;71:1134-40.
7. Laursen S B, Dalton H R, Murray I A, et al. Performance of new thresholds of the Glasgow Blatchford score in managing patients with upper gastrointestinal bleeding(J). Clin Gastroenterol Hepatol, 2015,13(1):115-121.
8. Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding. González-González JA, Vázquez-Elizondo G, García-Compeán D, Gaytán-Torres JO, Flores-Rendón ÁR, Jáquez-Quintana JO, Garza-Galindo AA, Cárdenas-Sandoval MG, Maldonado-Garza HJ. Rev Esp Enferm Dig. 2011 Apr;103(4):196-203. English, Spanish.
9. Blatchford O, Murray W R, Blatchford M. A risk score to predict need for treatment for upper-gastrointestinal haemorrhage(J). Lancet, 2000,356(9238):1318-1321.
10. Rockall T A, Logan R F, Devlin H B, et al. Risk assessment after acute upper gastrointestinal haemorrhage(J). Gut, 1996,38(3):316-321.
11. The predictive capacity of the Glasgow-Blatchford score for the risk stratification of upper gastrointestinal bleeding in an emergency department. Recio-Ramírez JM, Sánchez-Sánchez Mdel P, Peña-Ojeda JA, Fernández-Romero E, Aguilera-Peña M, del-Campo-Molina E, Zambrana-García JL. Rev Esp Enferm Dig. 2015 May;107(5):262-7.
12. Saltzman J R, Tabak Y P, Hyett B H, et al. A simple risk score accurately predicts in-hospital mortality, length of stay, and cost in acute upper GI bleeding(J). Gastrointest Endosc, 2011,74(6):1215-1224.
13. Jung S H, Oh J H, Lee H Y, et al. Is the AIMS65 score useful in predicting outcomes in peptic ulcer bleeding?(J). World J Gastroenterol, 2014,20(7):1846-1851.
14. Chen I C, Hung M S, Chiu T F, et al. Risk scoring systems to predict need for clinical intervention for patients with nonvariceal upper gastrointestinal tract bleeding(J). Am J Emerg Med, 2007,25(7):774-779.
15. Romagnuolo J, Barkun A N, Enns R, et al. Simple clinical predictors may obviate urgent endoscopy in selected patients with nonvariceal upper gastrointestinal tract bleeding(J). Arch Intern Med, 2007,167(3):265-270.
16. Yaka E, Yilmaz S, Dogan N O, et al. Comparison of the Glasgow-Blatchford and AIMS65 scoring systems for risk stratification in upper gastrointestinal bleeding in the emergency department(J). Acad Emerg Med, 2015,22(1):22-30.
17. Wang Haiyan, Dun Xiaotong, Bai Yuqi et al. Clinical epidemiological analysis of upper gastrointestinal bleeding in China(J).Chinese Journal of Digestive Endoscopy, 2013, 30(2):83~86.
18. Gu L, Xu F, Yuan J, et al. Comparison of AIMS65, Glasgow-Blatchford and Rockall scoring approaches in predicting the risk of in-hospital death among emergency hospitalized patients with upper gastrointestinal bleeding: a retrospective observational study in Nanjing, China(J). BMC Gastroenterology, 2018, 18(98).
19. Thandassery RB, Sharma M, John AK, et al. Clinical Application of AIMS65 Scores to Predict Outcomes in Patients with Upper Gastrointestinal Hemorrhage(J). Gastrointestinal Endoscopy, 2015, 48(5):380-384.
20. Stanley AJ,Laine L,Dalton HR, et al. Comparison of risk scoring systems for patients presenting with upper gastrointestinal bleeding: international multicentre prospective study(J). BMJ-BRITISH MEDICAL JOURNAL, 2017, 365, i6432.
21. Abougergi MS, Charpentier, JP, Bethea, E, et al. A Prospective, Multicenter Study of the AIMS65 Score Compared With the Glasgow-Blatchford Score in Predicting Upper Gastrointestinal Hemorrhage Outcomes(J). JOURNAL OF CLINICAL GASTROENTEROLOGY. 2016,50(6):464-469.
22. Tang YD, Shen J, Zhang F, et al. Scoring systems used to predict mortality in patients with acute upper gastrointestinal bleeding in the ED(J). AMERICAN JOURNAL OF EMERGENCY MEDICINE, 2017, 36(1):27-32.
23. Rout Gyanranjan, Sharma Sanchit, Gunjan Deepak, et al. Comparison of various prognostic scores in variceal and non-variceal upper gastrointestinal bleeding: A prospective cohort study(J). Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology.2019,05,(04).
24. Thanapirom K, Ridtitid W, Rerknimitr R, et al. Prospective comparison of three risk scoring systems in non-variceal and variceal upper gastrointestinal bleeding(J). JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2016, 31(4):761-767.
25. Kumar N L, Claggett B L, Cohen A J, et al. Association between an increase in blood urea nitrogen at 24 hours and worse outcomes in acute nonvariceal upper GI bleeding(J). Gastrointest Endosc, 2017,86(6):1022-1027.
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Lu X, Zhang X, Chen H. Comparison of the AIMS65 score with the Glasgow-Blatchford and Rockall scoring systems for the prediction of the risk of in-hospital death among patients with upper gastrointestinal bleeding. 6496/2019


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Publication history

Received: 11/07/2019

Accepted: 29/12/2019

Online First: 07/05/2020

Published: 08/06/2020

Article revision time: 156 days

Article Online First time: 301 days

Article editing time: 333 days


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