Year 2021 / Volume 113 / Number 9
Letter
Primary Ewing's sarcoma of the small intestine

680

DOI: 10.17235/reed.2021.7735/2020

José Joaquín Paricio, Juan Ruiz Martín, Esther Sánchez Díaz,

Abstract
17 year old female teenager with abdominal pain secondary to pelvic mass of 12 x 10 cm, which seems to depend on ovary. Surgery is scheduled for removal of the tumor, during which it is observed that the lesion originates in the ileum. The histopathological study shows a neoplasm of small round cells with nucleoli and scant cytoplasm. The tumor cells are immunoreactive to CD99 and ERG, being negative for cytokeratins, FLI1, WT1, DOG1 and lymphoid markers. By means of FISH, a rearrangement of the EWSR1 gene was demonstrated. By integrating these molecular and immunohistochemical findings with the morphology, it was diagnosed as Ewing's sarcoma. This aggressive and infrequent tumor originates from neuroectodermal cells and usually develops in the long bones of pediatric and young adult patients, although exceptionally it can occur in other locations. At the intestinal level, it mainly affects the ileum, with a non-specific pain and fatigue clinic. The treatment of choice is surgery for resection of the affected loop, followed by chemotherapy.
Share Button
New comment
Comments
No comments for this article
References
1. Cantu C, Bressler E, Dermawan J, et al. Ewing sarcoma of the jejunum: A case report. Perm J 2019;23:18-255. DOI: 10.7812/TPP/18-255
2. Li T, Zhang F, Cao Y, et al. Primary Ewing's sarcoma/primitive neuroectodermal tumor of the ileum: case report of a 16-year-old Chinese female and literature review. Diagn Pathol 2017;12(1):37. DOI: 10.1186/s13000-017-0626-3
3. Kolosov A, Dulskas A, Pauza K, et al. Primary Ewing's sarcoma in a small intestine - a case report and review of the literature. BMC Surg 2020;20(1):113. DOI: 10.1186/s12893-020-00774-z
4. Milione M, Gasparini P, Sozzi G, et al. Ewing sarcoma of the small bowel: a study of seven cases, including one with the uncommonly reported EWSR1-FEV translocation. Histopathology 2014;64(7):1014-26. DOI: 10.1111/his.12350
5. Pérez Fernández A, Sánchez Melgarejo JF, Rubio Mateos JM. Rhabdoid cavitated adenocarcinoma in the jejunum, an exceptional case by enteroscopy. Rev Esp Enferm Dig 2020;112(4):327. DOI: 10.17235/reed.2020.6425/2019
Related articles

Letter

Extensive small intestinal diffuse large B cell lymphoma

DOI: 10.17235/reed.2022.9100/2022

Letter

Primary intestinal melanoma?

DOI: 10.17235/reed.2022.8944/2022

Letter

Bowel angioedema induced by iodinated contrast media

DOI: 10.17235/reed.2022.8627/2022

Letter

Adenocarcinoma of the small intestine in Crohn's disease

DOI: 10.17235/reed.2021.8050/2021

Digestive Diseases Image

Metastasis of dermatofibrosarcoma diagnosed by capsule endoscopy

DOI: 10.17235/reed.2018.4900/2017

Citation tools
Paricio J, Ruiz Martín J, Sánchez Díaz E. Primary Ewing's sarcoma of the small intestine. 7735/2020


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 440 visits.
This article has been downloaded 106 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 16/12/2020

Accepted: 25/12/2020

Online First: 25/01/2021

Published: 07/09/2021

Article Online First time: 40 days

Article editing time: 265 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology