Year 2023 / Volume 115 / Number 7
Digestive Diseases Image
Intestinal and perianal tuberculosis: an uncommon clinical presentation and challenging diagnosis

387-388

DOI: 10.17235/reed.2022.8988/2022

Cristiana Sequeira, Mariana Coelho, João Mangualde, Ana Paula Oliveira,

Abstract
We present the case of a 40-year-old immunocompetent man with complaints of perianal abscess, diarrhea, and weight loss for 3 months. He denied respiratory symptoms. Colonoscopy revealed ulcers and histopathology showed non-necrotizing granulomas and excluded acid-fast bacilli. Initially, the clinical and histological findings favored the diagnosis of Crohn's disease, however, further investigation by performing chest radiography in the context of a pre-immunomodulatory checklist, revealed pulmonary cavitations confirmed on computed tomography scan. Further mycobacteriological studies suggested the diagnosis of active pulmonary tuberculosis. Demonstration of the presence of Mycobacterium tuberculosis in the colon was possible by RT-PCR. Complete resolution of intestinal and perianal symptoms was achieved 2 weeks after treatment with anti-bacillary agents.
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References
1. Eraksoy H. Gastrointestinal and Abdominal Tuberculosis. Gastroenterology Clinics of North America. 2021 Jun;50(2):341–60.
2. Tago S. Perianal tuberculosis: A case report and review of the literature. WJCC. 2015;3(9):848.
3. Kedia S, Das P, Madhusudhan KS, Dattagupta S, Sharma R, Sahni P, et al. Differentiating Crohn’s disease from intestinal tuberculosis. WJG. 2019 Jan 28;25(4):418–32.
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Sequeira C, Coelho M, Mangualde J, Oliveira A. Intestinal and perianal tuberculosis: an uncommon clinical presentation and challenging diagnosis. 8988/2022


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Publication history

Received: 05/06/2022

Accepted: 19/06/2022

Online First: 24/06/2022

Published: 06/07/2023

Article revision time: 5 days

Article Online First time: 19 days

Article editing time: 396 days


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