Year 2022 / Volume 114 / Number 3
Digestive Diseases Image
Malignancy of intraductal papillary neoplasm of the bile duct

170-171

DOI: 10.17235/reed.2021.8193/2021

Ana Aparicio Serrano, Alberto Gómez Pérez, Javier Manuel Zamora Olaya, Manuel Luis Rodríguez Perálvarez,

Abstract
Intraductal papillary neoplasm of the bile duct (IPNB) is an uncommon disease which was first included in the World Health Organization classification of neoplasms in 2010. A 64-year-old female was admitted to the hospital because of a hepatic lesion incidentally diagnosed during acute cholangitis. Abdominal computed tomography (CT) and magnetic resonance imaging (MRI) showed a well delimited 70 mm mass, with a predominant cystic component and hyperenhancement of papillary internal branching, consistent with a hydatid cyst. However, malignancy could not be excluded. The patient rapidly developed an acute abdomen syndrome, thus precluding a liver biopsy. A new urgent CT was performed to rule out a complication of the cystic lesion. A left hepatectomy was performed and the anatomopathological study confirmed the diagnosis of IPNB with a focus of cholangiocarcinoma therein. During follow up, the patient developed peritoneal carcinomatosis, received palliative chemotherapy and finally died.
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References
1. Nakanuma Y, Uesaka K, Kakuda Y, et al. Intraductal Papillary Neoplasm of Bile Duct: Updated Clinicopathological Characteristics and Molecular and Genetic Alterations. J Clin Med. 2020;9(12):3991.
2. Bill JG, Chaterjee D, Mullady DK. Using peroral cholangioscopy to diagnose an intraductal papillary neoplasm of the bile duct. VideoGIE. 2020 Jan 12;5(2):68-71.
3. Martí Fernández R, Garcés Albir M, Ballester MP, et al. Surgical treatment of an intraductal papillary mucinous neoplasm of the biliary tract diagnosed by SpyGlass®. Rev Esp Enferm Dig. 2021 Jan;113(1):45-7.
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Aparicio Serrano A, Gómez Pérez A, Zamora Olaya J, Rodríguez Perálvarez M. Malignancy of intraductal papillary neoplasm of the bile duct . 8193/2021


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Publication history

Received: 04/07/2021

Accepted: 20/07/2021

Online First: 24/08/2021

Published: 07/03/2022

Article revision time: 13 days

Article Online First time: 51 days

Article editing time: 246 days


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