Year 2017 / Volume 109 / Number 4
Editorial
Target population for the screening of human papillomavirus (HPV) and anal carcinoma precursor lesions – Results from a pilot study in HIV-infected males with sexual risk factors

241

DOI: 10.17235/reed.2017.4939/2017

Carlos Pastor, Alfonso Cabello Úbeda,

Abstract
Ninety-five percent of precursor lesions –high-grade squamous intraepithelial lesions (HSIL) and anal intraepithelial neoplasms (AIN)– and their progression to squamous anal cancer (AC) are induced by high-risk HPV (HR-HPV) serotypes 16 and 18. Their incidence is higher particularly in HIV-infected male patients who have sex with other males (HIV-MSM) (144/100,000/patients/year).
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References
1. Bosch FX, Brocker TR, Forman D, et al. Comprehensive control of human papillomavirus infections and related diseases. Vaccine. 2013;31 (Suppl 7)
2. Johnson LG, Madeleine MM, Newcomer LM, et al.: the surveillance, epidemiology, and end results experience, 1973-2000. Cancer. 2004;101(2):281–8.
3. Machalek D a, Poynten M, Jin F, et al. Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysis. Lancet Oncol. 2012;22(12):1–14.
4. Abramowitz L, Benabderrahmane D, Ravaud P, et al. Anal squamous intraepithelial lesions and condyloma in HIV-infected heterosexual men, homosexual men and women: prevalence and associated factors. AIDS. 2007;21:1457–65.
5. Referencia del artículo referenciado en la Editorial.
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Pastor C, Cabello Úbeda A. Target population for the screening of human papillomavirus (HPV) and anal carcinoma precursor lesions – Results from a pilot study in HIV-infected males with sexual risk factors. 4939/2017


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Publication history

Received: 07/03/2017

Accepted: 08/03/2017

Online First: 17/03/2017

Published: 31/03/2017

Article Online First time: 10 days

Article editing time: 24 days


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